The Prognostic Value of Osmolality Within the First Week of Sustaining Head Injury

  • M. Gaab
  • H. A. Trost
  • K. W. Pflughaupt
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 28)


On sustaining severe brain damage, there generally follow disturbances of metabolic regulation. The latter is a central function of the diencephalon10 and brain stem7. Thus several groups have monitored various blood metabolites e.g. hyperglycaemia12, azotaemia2, lactatepyruvate8, proteins2, 4 and lipids3 with regard to prognosis after head injury. However, though mentioned2,12, blood and CSF osmolality have not been systematically investigated despite the known role of the diencephalon in osmoregulation13,15 . We therefore investigated the course of blood and CSF osmolalities, correlating them with clinical and other biochemical data.


Head Injury Plasma Osmolality Severe Head Injury Severe Brain Injury Urine Specific Gravity 
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Copyright information

© Springer-Verlag Wien 1979

Authors and Affiliations

  • M. Gaab
    • 1
  • H. A. Trost
    • 1
  • K. W. Pflughaupt
    • 1
  1. 1.Neurosurgical Clinic of the University of WürzburgFederal Republic of Germany

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