The Significance of Cerebral and Systemic Disseminated Intravascular Coagulation in Early Prognosis of Brain Injury

  • A. Tikk
  • U. Noormaa
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 28)


The main aim of the present investigation is to resolve the dynamics of local cerebral and systemic coagulation disorders, and to evaluate their significance in early prognosis of brain injury. The investigation was carried out in 92 patients with brain injury as follows: 10 patients with brain concussion and slight brain contusion, 12 patients with moderate brain contusion, 34 patients with severe brain contusion together with great neurological deficit, and 36 patients with fatal brain contusion, 24 of whom died in the first week of illness and 12 stayed in an apallic state and died some months or some years after brain injury. Platelet counts, intravascular platelet aggregation, fibrinogen concentration, paracoagulation tests for soluble fibrin, whole blood fibrinolytic activity (FA), electrocoagulography (EC), and thromboelastography (TEG) in systemic venous and arterial as well as in cerebral venous blood were performed. The data were compared with controls.


Brain Injury Disseminate Intravascular Coagulation Fibrinolytic Activity Fibrinogen Concentration Severe Brain Injury 
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Copyright information

© Springer-Verlag Wien 1979

Authors and Affiliations

  • A. Tikk
    • 1
  • U. Noormaa
    • 1
  1. 1.Department of Neurology and Neurosurgery and Cerebrovascular Research LaboratoryFaculty of Medicine, State University of TartuEstonia, USSR

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