Among the reasons for intensified research into the CSF haemostatic pathway were the clinical case reports stating that special importance must be attached to the CSF for the high incidence of rebleeding and the intraoperative haemorrhage rate in SAH patients, which, among other things, may be regarded as the reasons for mortality. Extensive analyses of the coagulation and fibrinolysis enzyme systems were carried out and constitute the basic concept for the conservative AFT aiming at restoring to normal haemostasis and wound healing which had been disturbed by local fibrinolytic activity in the area of operation or trauma.
KeywordsDisseminate Intravascular Coagulation Fibrinolytic Activity Clinical Case Report Normal Haemostasis Antifibrinolytic Drug
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