Chordoma is a low-grade malignant tumor originating from remnants of the notochord.


Fibrous Septum Neural Canal Extraskeletal Myxoid Chondrosarcomas Myxoid Chondrosarcomas Sacral Foramina 
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  1. 1967.
    Higinbotham N.L., Phillips R.F., Farr H.W., Hustu H.O. (1967): Chordoma. Thirty-five years study at Memorial Hospital. Cancer, 20, 1841–1850.PubMedCrossRefGoogle Scholar
  2. 1967.
    LoCalio S.A., Francis K.C., Rossano P.G. (1967): Abdominosacral resection of sacrocóccygeal chordoma. Ann. Surg., 166, 394–402.CrossRefGoogle Scholar
  3. 1968.
    Anderson W.B., Meyers H.I. (1968): Multicentric chordoma. Report of a case. Cancer, 21, 126–128.PubMedCrossRefGoogle Scholar
  4. 1970.
    Murad T.M., Murthy M.S. (1970): Ultrastructure of a chordoma. Cancer, 25, 1204–1215.PubMedCrossRefGoogle Scholar
  5. 1973.
    Heffelfinger J.M., Dahlin D.C., Mc Carty C.S., Beabout J.W. (1973): Chordomas and cartilaginous tumors at the skull base. Cancer, 32, 410–420.PubMedCrossRefGoogle Scholar
  6. 1978.
    Stener B., Gunterberg B. (1978): High amputation of the sacrum for extirpation of tumors. Principles and technique. Spine, 3, 351–366.PubMedCrossRefGoogle Scholar
  7. 1979.
    Sundaresan N., Galicich J.H., Chu F.C.H., HUvoS A.G. (1979): Spinal chordomas. J. Neurosurg., 50, 31 2319.Google Scholar
  8. 1981.
    Mindell E.R. (1981): Chordoma. J. Bone Joint Surg., 63-A, 501–505.Google Scholar
  9. 1981.
    Pardo-Mindan F.J., Guillen F.J., Villas C., Vazquez J.J. (1981): A comparative ultrastructural study of chondrosarcoma, chondroid sarcoma and chordoma. Cancer, 47, 2611–2619.CrossRefGoogle Scholar
  10. 1982.
    Ulich T.R., Mirra J.M. (1982): Ecchordosis physaliphora vertebralis. Clin. Orthop., 163, 282–289.PubMedGoogle Scholar
  11. 1983.
    Wold L.E., Laws E.R.Jr. (1983): Cranial chordomas in children and young adults. J. Neurosurg., 59, 1043–1047.PubMedCrossRefGoogle Scholar
  12. 1984.
    Meyer J.E., Lepke R.A., Lindfors K.K., Pagani J.J., Hirschy J.C., Hayman L.A., Momose K.J., McGinnis G. (1984): Chordomas: their CT appearance in the cervical, thoracic, and lumbar spine. Radiology, 153, 693–696.Google Scholar
  13. 1985.
    Rich T.A., Schiller A., Suit H.D., Mankin H.J. (1985): Clinical and pathologic review of 48 cases of chordoma. Cancer, 56, 182–187.PubMedCrossRefGoogle Scholar
  14. 1985.
    Rosenthal D.I., Scott J.A., Mankin H.J., Wismer G.L., Brady T.J. (1985): Sacrococcygeal chordoma: magnetic resonance imaging and computed tomography. Am. J. Roentgenol., 145, 143–147.CrossRefGoogle Scholar
  15. 1985.
    Salisbury J.R., Isaacson P.G. (1985): Demonstration of cytokeratins and an epithelial membrane antigen in chordomas and human fetal notochord. Am. J. Surg. Pathol., 9, 791–797.PubMedCrossRefGoogle Scholar
  16. 1987.
    Chiras J., Gagna G., Rose M., Saillant G., Bories J., Roy-Camille R. (1987): Arteriographie et embolisation des tumeurs du sacrum. Rev. Chir. Orthop., 73, 99–103.Google Scholar
  17. 1987.
    Meis J.M., Raymond A.K., Evans H.L., Charles R.E., Giraldo A.A. (1987): “Dedifferentiated” chordoma. Aclinicopathologic and immunohistochemical study of three cases. Am. J. Surg. Pathol., 11, 516–525.Google Scholar
  18. 1987.
    Smith J., Ludwig R.L., Marcove R.C. (1987): Sacrococcygeal chordoma. A clinicoradiological study of 60 patients. Skeletal Radiol., 16, 37–44.PubMedCrossRefGoogle Scholar
  19. 1987.
    Stener B. (1987): Traitement chirurgical des tumeurs du sacrum. Rev. Chir. Orthop., 73, 114–121.PubMedGoogle Scholar
  20. 1989.
    Smith J., Reuter V., Demas B. (1989): Case report 576.Anaplastic sacrococcygeal chordoma (dedifferentiated chordoma). Skeletal Radiol., 18, 561–564.PubMedCrossRefGoogle Scholar
  21. 1990.
    Hruban R.H., Traganos F., Reuter V.E., Huvos A.G. (1990): Chordomas with malignant spindle cell components. A Dna flow-cytometric and immunohistochemical study with histogenetic implications. Am. J. Pathol., 137, 435–447.PubMedGoogle Scholar
  22. 1990.
    Tomita K., Tsuchiya H. (1990): Total sacrectomy and reconstruction for huge sacral tumors. Spine, 15, 1223–1227.PubMedCrossRefGoogle Scholar
  23. 1991.
    Ducon LE Pointe H., Brugieres P., Chevalier X., Meder J.F., Voisin M.C., Gaston A. (1991): Imaging of chordomas of the mobile spine. J. Neuroradiol., 18, 267–276.Google Scholar
  24. 1991.
    Keisch M.E., Garcia D.M., Shibuya R.B. (1991): Retrospective long-term follow-up analysis in 21 patients with chordomas of various sites treated at a single institution. J. Neurosurg., 75, 374–377.PubMedCrossRefGoogle Scholar
  25. 1991.
    Persson S., Kindblom L.G., Angervall L. (1991): Classical and chondroid chordoma. A light-microscopic, histochemical, ultrastructural and immunohistochemical analysis of the various cell types. Pathol. Res. Pract., 187, 828–838.PubMedCrossRefGoogle Scholar
  26. 1991.
    Walaas L., Kindblom L.G. (1991): Fine-needle aspiration biopsy in the preoperative diagnosis of chordoma. A study of 17 cases with application of electron microscopic, histochemical, and immunohistochemical examination. Hum. Pathol., 22, 22–28.PubMedCrossRefGoogle Scholar
  27. 1991.
    Walker W.P., Landas S.K., Bromley C.M., Sturm M.T.: Immunohistochemical distinction of classic and chondroid chordomas. Mod. Pathol., 4, 661–666.Google Scholar
  28. 1992.
    Nowakowski V.A., Castro J.R., Petti P.L., Collier J.M., Daftari I., Ahn D., Gauger G., Gutin P., Linstadt D.E., Phillips T.L.: Charged particle radiotherapy of paraspinal tumors. Int. J. Radiat. Oncol. Biol. Phys., 22, 295–303.Google Scholar
  29. 1992.
    Wojno K.J., Hruban R.H., Garin-Chesa P., Huvos A.G. (1992): Chondroid chordomas and low-grade chondrosarcomas of the craniospinal axis. An immunohistochemical analysis of 17 cases. Am. J. Surg. Pathol., 16, 1144–1152.PubMedCrossRefGoogle Scholar
  30. 1993.
    Austin J.P., Urie N.M., Cardenosa G., Munzenrider J.E. (1993): Probable causes of recurrence in patients with chordoma and chondrosarcoma of the base of the skull and cervical spine. Int. J. Radiat. Oncol. Biol. Phys., 25, 439–444.PubMedCrossRefGoogle Scholar
  31. 1993.
    Bjornsson J., Wold L.E., Ebersold M.J., Laws E.R. (1993): Chordoma of the mobile spine. A clinicopathologic analysis of 40 patients. Cancer, 71, 735–740.PubMedCrossRefGoogle Scholar
  32. 1993.
    Coffin C.M., Swanson P.E., Wick M.R., Dehner L.P. (1993): Chordoma in childhood and adolescence. A clinicopathologic analysis of 12 cases. Arch. Pathol. Lab. Med., 117, 927–933.PubMedGoogle Scholar
  33. 1993.
    Fleming G.F., Heimann P.S., Stephens J.K., Simon M.A., Ferguson M.K., Benjamin R.S., Samuel B.L. (1993): Dedifferentiated chordoma. Response to aggressive chemotherapy in two cases. Cancer, 72, 714718.Google Scholar
  34. 1993.
    Mitchell A., Scheithauer B.W., Unni K.K., Forsyth P.J., Wold L.E., MC Givney D.J. (1993): Chordoma and chondroid neoplasms of the spheno-occiput. An immunohistochemical study of 41 cases with prognostic and nosologic implications. Cancer, 72, 2943–2949.PubMedCrossRefGoogle Scholar
  35. 1993.
    Samson I.R., Springfield D.S., Suit H.D., Mankin H.J. (1993): Operative treatment of sacrococcygeal chordoma. A review of twenty-one cases. J. Bone Joint Surg., 75-A, 1476–1484.Google Scholar
  36. 1994.
    O’Connell J.X., Renard L.G., Liebsch N.J., Efird J.T., Munzenrider J.E., Rosenberg A.E. (1994): Base of skull chordoma. A correlative study of histologic and clinical features of 62 cases. Cancer, 74, 22612267.Google Scholar
  37. 1994.
    Rosenberg A.E., Brown G.A., Bhan A.K., Lee J.M. (1994): Chondroid chordoma: a variant of chordoma. A morphologic and immunohistochemical study. Am. J. Clin. Pathol., 101, 36–41.PubMedGoogle Scholar
  38. 1994.
    Shin H.J., Mackay B., Ichinose H., Ayala A.G., Romsdahl M.M(1994).: Parachordoma. Ultrastruct. Pathol., 18, 249–256.Google Scholar
  39. 1995.
    Fagundes M.A., Hug E.B., Liebsch N.J., Daly W., Efird J., Munzenrider J.E. (1995): Radiation therapy for chordomas of the base of skull and cervical spine: patterns of failure and outcome after relapse. Int. J. Radiat. Oncol. Biol. Phys., 33, 579–584.PubMedCrossRefGoogle Scholar
  40. 1995.
    Jeffrey P.B., Biava C.G., Davis R.L. (1995): Chondroid chordoma. A hyalinized chordoma without cartilaginous differentiation. Am. J. Clin. Pathol., 103, 271–279.PubMedGoogle Scholar
  41. 1995.
    Simpson A.H., Porter A., Davis A., Griffin A., McLeod R.S. Bell R.S. (1995): Cephalad sacral resection with a combined extended ilioinguinal and posterior approach. J. Bone Joint Surg., 77-A, 405–411.Google Scholar
  42. 1996.
    Boriani S., Chevalley F., Weinstein J.N., Biagini R., Campanacci L., DE Iure F., Picci P. (1996): Chordoma of the spine above the sacrum. Treatment and outcome in 21 cases. Spine, 21, 1569–1577.PubMedCrossRefGoogle Scholar
  43. 1996.
    Catton C., O’Sullivan B., Bell R., Laperriere N., Cummings B., Fornasier V., Wunder J. (1996): Chordoma: long-term follow-up after radical photon irradiation. Radiother. Oncol., 41, 67–72.Google Scholar
  44. 1996.
    Chandawarkar R.Y. (1996): Sacrococcygeal chordoma: review of 50 consecutive patients. World J. Surg., 20, 717–719.PubMedCrossRefGoogle Scholar
  45. 1996.
    Crockard A. (1996): Chordomas and chondrosarcomas of the cranial base: results and follow-up of 60 patients. Neurosurgery, 38, 420.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Wien 1999

Authors and Affiliations

  • Mario Campanacci
    • 1
    • 2
  1. 1.University of BolognaItaly
  2. 2.Rizzoli Orthopaedic InstituteBolognaItaly

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