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Giant Cell Tumor

Giant Cell Tumor of Bone, Osteoclastoma
  • Mario Campanacci

Abstract

Giant cell tumor of bone is defined as an intramedullary bone tumor, with a specific predilection for age and location, composed of mononucleated cells and osteoclast-like multi-nucleated giant cells, and having a variable and unpredictable potential for growth1. The giant cell tumor usually behaves as a benign tumor, but has a significant tendency to recur locally and, rarely, may produce pulmonary metastases. These have the same histological features as the primary tumor and are frequently curable. Rarely, a giant cell tumor may transform into a high-grade sarcoma.

Keywords

Local Recurrence Giant Cell Pulmonary Metastasis Pathologic Fracture Multinucleated Giant Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Wien 1999

Authors and Affiliations

  • Mario Campanacci
    • 1
    • 2
  1. 1.University of BolognaItaly
  2. 2.Rizzoli Orthopaedic InstituteBolognaItaly

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