Abstract
This is a difficult chapter, because: a) several Authors question the term of “benign hemangioendothelioma” and prefer to name it angioma (epithelioid, histiocytoid, cellular). b) Although benign and highly malignant (angiosarcoma) hemangioendotheliomas are clearly distinguishable, it is more difficult and uncertain to recognize the intermediate seemingly low-grade tumors. It is also uncertain whether a progression of malignancy can occur in low-grade hemangioendothelioma.
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References
Hartmann W.H., Stewart F.W.: Hemangioendothelioma of bone. Unusual tumor characterized by indolent course. Cancer, 15, 846–854.
Zanasi R.: Endotelioma benigno dello scheletro. Arch. Ortop., 77, 41–47.
Bundens W.D., Brighton C.T.: Malignant hemangioendothelioma of bone. Report of two cases and review of the literature. J. Bone Joint Surg., 47-A, 762–772.
Otis J., Hutter R.V., Foote F.W.Jr., Marcove R.C., Stewart F.W.: Hemangioendothelioma of bone. Surg. Gynecol. Obstet., 127, 295–305 1968.
Campanacci M., Cenni F., Giunti A.: Angectasie, amartomi e neoplasie vascolari dello scheletro. Chir. Organi Mov., 58, 472–498.
Dorfman H.D., Steiner G.C., Jaffe H.L.: Vascular tumours of bone. Hum. Pathol., 2, 349–376.
Unni K.K., Ivins J.C., Beabout J.W., Dahlin D.C.: Hemangioma, hemangiopericytoma and hemangioendothelioma (angiosarcoma) of bone. Cancer, 27, 1403–1414.
Dube V.E., Fisher D.E.: Hemangioendothelioma of the leg following metallic fixation of the tibia. Cancer, 30, 1260–1266.
Steiner G.C., Dorfman H.D.: Ultrastructure of hemangioendothelial sarcoma of bone. Cancer, 29, 122–135.
Larsson S.E., Lorentzon R., Boquist L.: Malignant hemangioendothelioma of bone. J. Bone Joint Surg., 57-A, 84–89.
Craver W.L., Brown B.S.: Hemangioendothelioma of bone with pulmonary metastases: a 25-year course. Report of a case. Cancer, 43, 1917–1923.
Campanacci M., Boriani S., Giunti A.: Hemangioendothelioma of bone. A study of 29 cases. Cancer, 46, 804–814.
Volpe R., Mazabraud A.: Hemangioendothelioma (angiosarcoma) of bone: a distinct pathologic entity with an unpredictable course. Cancer, 49, 727–736.
Wold L.E., Unni K.K., Beabout J.W., Ivins J.C., Bruckman J.E., Dahlin D.C.: Hemangioendothelial sarcoma of bone. Am. J. Surg. Pathol., 6, 59–70.
Mirra J.M., Kameda N.: Case report 366. Myxoid angioblastomatosis of bone (disseminated). Skeletal Radiol., 15, 323–326 1986.
Tsuneyoshi M., Dorfman H.D., Bauer T.W.: Epithelioid hemangioendothelioma of bone. A clinicopa-thologic, ultrastructural and immunohistochemical study. Am J. Surg. Pathol., 10, 754–764 1986.
Van Der List J.J., Van Horn J.R., Slooff T.J., Cate L.N.: Malignant epithelioid hemangioendothe-lioma at the site of a hip prosthesis. Acta Orthop. Scand., 59, 328–330.
De Smet A.A., Inscore D., Neff J.R.: Case report 521. Histiocytoid hemangioma of the distal end of the right humerus. Skeletal Radiol., 18, 60–65.
Martinez-Tello F.J., Marcos-Robles J., Blanco-Lorenzo F.: Case report 520. Primary epithelioid hemangioendothelioma of bone (polyostotic). Skeletal Radiol., 18, 55–59 1989.
Van Haelst U.J., Pruszczynsky M., Cate L.N., Mravunac M.: Ultrastructural and immunohistochemical study of epithelioid hemangioendothelioma of bone: coexpression of epithelial and endothelial markers. Ultrastruct. Pathol., 14, 141–149.
Abdelwahab I.F., Kenan S., Klein M.J., Lewis M.M.: Case report: angiosarcoma occurring in a bone infarct. Clin. Radiol., 45, 412–414.
Abrahams T.G., Bula W., Jones M.: Epithelioid hemangioendothelioma of bone. A report of two cases and review of the literature. Skeletal Radiol., 21, 509–513.
Carmody E., Lofrus B., Corrigan J., O’sullivan T., Leader M., Keeling F.: Case report 759. Malignant epithelioid hemangioendothelioma of bone. Skeletal Radiol., 21, 538–541.
Mcnamara D., Beauregard G.C., Lemieux R.J.: Schintigraphic “doughnut sign” on skeletal imaging due to a hemangioendothelioma of bone. J. Nucl. Med., 34, 297–300.
O’connell J.X., Kattapuram S.V., Mankin H.J., Bhan A.K., Rosenberg A.E.: Epithelioid hemangioma of bone. A tumor often mistaken for low-grade angiosarcoma or malignant hemangioendothelioma. Am. J. Surg. Pathol., 17, 610–617 1993.
Tsang W.Y., Chan J.K.: The family of epithelioid vascular tumors. Histol. Histopathol., 8, 187–212.
Bollinger B.K., Laskin W.B., Knight C.B.: Epithelioid hemangioendothelioma with multiple site involvement. Literature review and observations. Cancer, 73, 610–615.
Welles L., Dorfman H., Valentine E.S., Wiernik P.H.: Low grade malignant hemangioendothelioma of bone: a disease potentially curable with radiotherapy. Med. Pediatr. Oncol., 23, 144–148.
Benassi M.S., Gamberi G., Ragazzini P., Sollazzo M.R., Ferrari C., Sangiorgi L., Trere D., Derenzini M., Picci P.: Bone hemangioendothelioma: an immunohistochemical study related to histological malignancy and proliferative activity (NORs). Tumori, 81, 179–184.
Pins M.R., Mankin H.J., Xavier R.J., Rosenthal D.I., Dickersin G.R., Rosenberg A.E.: Malignant epithelioid hemangioendothelioma of the tibia associated with a bone infarct in a patient who had Gaucher disease. A case report. J. Bone Joint Surg., 77-A, 777–781.
Kleer C.G., Unni K.K., Mcleod R.A.: Epithelioid hemangioendothelioma of bone. Am. J. Surg. Pathol., 20, 1301–1311.
Lamovec J., Bracko M.: Epithelioid hemangioma of small tubular bones: a report of three cases, two of them associated with pregnancy. Mod. Pathol., 9, 821–827.
Lomasney L.M., Martinez S., Demos T.C., Harrelson J.M.: Multifocal vascular lesions of bone: imaging characteristics. Skeletal Radiol., 25, 255–261.
Matsuno T., Kaneda K., Takeda N.: Development of angiosarcoma at the site of a bone infarct. Clin. Orthop., 327, 259–263.
Tillman R.M., Choong P.F., Beabout J.W., Wold L.E., Sim F.H.: Epithelioid hemangioendothelioma of bone. Orthopedics, 20, 177–180.
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Campanacci, M. (1999). Hemangioendothelioma, Benign. In: Bone and Soft Tissue Tumors. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3846-5_38
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DOI: https://doi.org/10.1007/978-3-7091-3846-5_38
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