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Osteoblastoma

  • Mario Campanacci

Abstract

It is a benign tumor composed of osteoblasts producing osteoid and bone. Its histology is usually similar to that of the osteoid osteoma, from which it is distinguished by symptoms, anatomo-imaging features and course. There are, however, transitional cases between an osteoid osteoma and an osteoblastoma (giant osteoid osteomas, rare cases of evolution from osteoid osteomas to osteoblastomas).

Keywords

Bone Tumor Giant Cell Tumor Osteoid Osteoma Aneurysmal Bone Cyst Permeative Pattern 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1954.
    Dahlin D.C., Johnson E.W. Jr.: 1954 Giant osteoid osteoma. J. Bone Joint Surg., 36A, 559–572.PubMedGoogle Scholar
  2. 1956.
    Jaffe H.L.: 1956 Benign osteoblastoma. Bull. Hosp. Joint Dis., 17, 141–151.PubMedGoogle Scholar
  3. 1956.
    Lichtenstein L.: 1956 Benign osteoblastoma. A category of osteoid and bone-forming other than classical osteoid osteoma, which may be mistaken for giant-cell tumor or osteogenic sarcoma. Cancer, 9, 1044–1052.PubMedCrossRefGoogle Scholar
  4. 1960.
    Pochaczevsky R., Yen Y.M., Sherman R.S.: 1960 The roentgen appearance of benign osteoblastoma. Radiology, 75, 429–437.PubMedGoogle Scholar
  5. 1964.
    Lichtenstein L., Sawyer W.R.: 1964 Benign osteoblastoma. Further observations and report of twenty additional cases. J. Bone Joint Surg., 46A, 755–765.PubMedGoogle Scholar
  6. 1967.
    Mayer L.: 1967 Malignant degeneration of socalled benign osteoblastoma. Bull. Hosp. Joint Dis., 28, 4–13.PubMedGoogle Scholar
  7. 1968.
    Byers P.D.: 1968 Solitary benign osteoblastic lesions of bone. Osteoid osteoma and benign osteoblastoma. Cancer, 22, 43–57.PubMedCrossRefGoogle Scholar
  8. 1970.
    Marsh H.O., Choi C.B.: 1970 Primary osteogenic sarcoma of the cervical spine originally mistaken for benign osteoblastoma. A case report. J. Bone Joint Surg., 52A, 1467–1471.PubMedGoogle Scholar
  9. 1970.
    Schajowicz F., Lemos C.: 1970 Osteoid osteoma and osteoblastoma. Closely related entities of osteoblastic derivation. Acta Orthop. Scand., 41, 272–291.PubMedCrossRefGoogle Scholar
  10. 1975.
    Marsh B.W., Bonfiglio M., Brady L.P., Enneking W.F.: 1975 Benign osteoblastoma: range of manifestations. J. Bone Joint Surg., 57A, 1–9.PubMedGoogle Scholar
  11. 1976.
    McLeod R.A., Dahlin D.C., Beabout J.W.: 1976 The spectrum of osteoblastoma. Am. J. Roentgenol., 126, 321–335.CrossRefGoogle Scholar
  12. 1976.
    Mirra J. M., Kendrick R. A., Kendrick R. E.: 1976 Pseudo-malignant osteoblastoma versus arrested osteosarcoma. A case report. Cancer, 37, 2005–2014.PubMedCrossRefGoogle Scholar
  13. 1976.
    Schajowicz F., Lemos C.: 1976 Malignant osteoblastoma. J. Bone Joint Surg., 58B, 202–211.Google Scholar
  14. 1977.
    Yoshikawa S., Nakamura T., Takagi M., Imamura T., Okano K., Sasaki A.: 1977 Benign osteoblastoma as a cause of osteomalacia. A report of two cases. J. Bone Joint Surg., 59B, 279–286.Google Scholar
  15. 1978.
    Boriani S., Campanacci M.: 1978 Osteoblastoma associated with osteomalacia. A case presentation review of the literature. Ital. J. Orthop. Traumatol., 4, 379–382.PubMedGoogle Scholar
  16. 1979.
    Mirra J.M., Theros E., Cove K., Paladugu R., Smasson J.: 1979 A case of osteoblastoma associated with severe systemic toxicity. Am. J. Surg. Pathol., 3, 463–471.PubMedCrossRefGoogle Scholar
  17. 1979.
    Sung H.W., Liu C.C.: 1979 Can osteoid osteoma become osteoblastoma? A case report. Arch. Orthop. Trauma Surg., 95, 217–219.PubMedCrossRefGoogle Scholar
  18. 1980.
    Merryweather R., Middlemiss J.H., Sanerkin N.G.: 1980 Malignant transformation of osteoblastoma. J. Bone Joint Surg., 65B, 381–384.Google Scholar
  19. 1982.
    Tonai M., Campbell C.J., Ahn G.H., Schiller A.L., Mankin H.J.: 1982 Osteoblastoma. Classification and report of 16 patients. Clin. Orthop., 167, 222–235.PubMedGoogle Scholar
  20. 1983.
    Pieterse A.S., Vernon-Roberts B., Paterson D.C., Cornish B.L., Lewis P.R.: 1983 Osteoid osteoma transforming to aggressive (low-grade malignant) osteoblastoma. A case report and literature review. Histopathology, 7, 789–800.PubMedCrossRefGoogle Scholar
  21. 1984.
    Dorfman H.D., Weiss S.W.: 1984 Borderline osteoblastic tumors. Problems in the differential diagnosis of aggressive osteoblastoma and low-grade osteosarcoma. Semin. Diagn. Pathol., 1, 215–234.PubMedGoogle Scholar
  22. 1984.
    Kirwan E.O., Hutton P.A.N., Pozo J.L., Ransford A.O.: 1984 Osteoid osteoma and benign osteoblastoma of the spine. J. Bone Joint Surg., 66B, 21–26.Google Scholar
  23. 1985.
    Bertoni F., Unni K.K., McLeod R.A., Dahlin D.C.: 1985 Osteosarcoma resembling osteoblastoma. Cancer, 55, 416–426.Google Scholar
  24. 1985.
    Kenan S., Floman Y., Robin G.C., Laufer A.: 1985 Aggressive osteoblastoma. A case report and review of the literature. Clin. Orthop., 195, 294–298.PubMedGoogle Scholar
  25. 1986.
    Capanna R., Ayala A., Bertoni F., Picci P., Calderoni P., Gherlinzoni F., Bettelli G., Campanacci M.: 1986 Sacral osteoid osteoma and osteoblastoma: a report of 13 cases. Arch. Orthop. Trauma Surg., 105, 205–210.PubMedCrossRefGoogle Scholar
  26. 1986.
    Healey J.H., Ghelman B.: 1986 Osteoid osteoma and osteoblastoma: current concepts and recent advances. Clin. Orthop., 204, 76–85.PubMedGoogle Scholar
  27. 1986.
    Pettine K.A., Klassen R.A.: 1986 Osteoid osteoma and osteoblastoma of the spine. J. Bone Joint Surg., 68, 354–361.PubMedGoogle Scholar
  28. 1989.
    Bettelli G., Capanna R., Van Horn J.R., Ruggieri P., Biagini R., Campanacci M.: 1989 Osteoid osteoma and osteoblastoma of the pelvis. Clin. Orthop., 247, 261–271.PubMedGoogle Scholar
  29. 1989.
    Gitelis S., Schajowicz F.: 1989 Osteoid osteoma and osteoblastoma. Orthop. Clin. North Am., 20, 313–325.Google Scholar
  30. 1989.
    Morton K.S., Quenville N.F., Beauchamp C.P.: 1989 Aggressive osteoblastoma. A case previously reported as a recurrent osteoid osteoma. J. Bone Joint Surg., 71B, 428–431.Google Scholar
  31. 1990.
    Crim J.R., Mirra J.M., Eckardt J.J., Seeger L.L.: 1990 Widespread inflammatory response to osteoblastoma: the flare phenomenon. Radiology, 177, 835–836.PubMedGoogle Scholar
  32. 1990.
    Kroon H.M., Schurmans J.: 1990 Osteoblastoma: clinical and radiologic findings in 98 new cases. Radiology, 175, 783–790.PubMedGoogle Scholar
  33. 1990.
    Nemoto O., Moser R.P.Jr. Van Dam B.E., Aoki J., Gilkey F.W.: 1990 Osteoblastoma of the spine. A review of 75 cases. Spine, 15, 1272–1280.PubMedCrossRefGoogle Scholar
  34. 1991.
    Bettelli G., Tigani D., Picci P.: 1991 Recurring osteoblastoma initially presenting as a typical osteoid osteoma. Report of two cases. Skeletal Radiol., 20, 1–4.PubMedCrossRefGoogle Scholar
  35. 1991.
    Camitta B., Wells R., Segura A., Unni K.K., Murray K., Dunn D.: 1991 Osteoblastoma response to chemotherapy. Cancer, 68, 999–1003.PubMedCrossRefGoogle Scholar
  36. 1992.
    Boriani S., Capanna R., Donati D., Levine A., Picci P., Savini R.: 1992 Osteoblastoma of the spine. Clin. Orthop., 278, 37–45.PubMedGoogle Scholar
  37. 1993.
    Bertoni F., Bacchini I., Donati D., Martini A., Picci P., Campanacci M.: 1993 Osteoblastoma-like osteosarcoma. The Rizzoli Institute experience. Mod. Pathol., 6, 707–716.PubMedGoogle Scholar
  38. 1993.
    Bertoni F., Unni K.K., Lucas D.R., McLeod R.A.: 1993 Osteoblastoma with cartilaginous matrix. An unusual morphologic presentation in 18 cases. Am. J. Surg. Pathol., 17, 69–74.Google Scholar
  39. 1993.
    O’Connell J.X., Rosenthal D.I., Mankin H.J., Gudger G.K., Dickers IN G.R., Schiller A.L., Rosenberg A.E.: 1993 A unique multifocal osteoblastoma-like tumor of the bones of a single lower extremity. Report of a case. J. Bone Joint Surg., 75-A, 597–602.Google Scholar
  40. 1993.
    Singer J.M., Deutsch G.P.: 1993 The successful use of radiotherapy for osteoblastoma. Clin. Oncol. R. Coll. Radiol., 5, 124–125.PubMedCrossRefGoogle Scholar
  41. 1994.
    Lee D.Y., Choi I.H., Lee C K, Chung C.Y., Cho K.H.: 1994 Acquired vitamin D-resistant rickets caused by aggressive osteoblastoma in the pelvis: a case report with ten years’ follow-up and review of the literature. J. Pediatr. Orthop., 14, 793–798.PubMedCrossRefGoogle Scholar
  42. 1994.
    Lucas D.R., Unni K.K., McLeod R.A., O’Connor M.I., Sim F.H.: 1994 Osteoblastoma. Clinicopathologic study of 306 cases. Hum. Pathol., 25, 117–134.PubMedCrossRefGoogle Scholar
  43. 1994.
    Zambelli P Y, Lechevallier J, Bracq H., Carlioz H.: 1994 Osteoid osteoma or osteoblastoma of the cervical spine in relation to the vertebral artery. J. Pediatr. Orthop., 14, 788–792.CrossRefGoogle Scholar
  44. 1996.
    Della Rocca C., Huvos A.G.: 1996 Osteoblastoma: varied histological presentations with a benign clinical course. An analysis of 55 cases. Am. J. Surg. Pathol., 20, 841–850.PubMedCrossRefGoogle Scholar
  45. 1997.
    Berberoglu S., Oguz A., Aribal E., Ataoglu O.: 1997 Osteoblastoma response to radiotherapy and chemotherapy. Med. Pediatr. Oncol., 28, 305–309.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Wien 1999

Authors and Affiliations

  • Mario Campanacci
    • 1
    • 2
  1. 1.University of BolognaItaly
  2. 2.Rizzoli Orthopaedic InstituteBolognaItaly

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