Hyperplasia is an accumulation of cells due to either accelerated proliferation or slowed maturation and degeneration. Hyperplasia is caused by a stimulus, and it ceases when the stimulus is exhausted. Hyperplasia is functional: as such, it has an organoid structure and it tends to differentiate and mature. Examples are exuberant bone callus, myositis ossificans, brown tumors in hyperparathyroidism, and, probably, aneurysmal bone cyst, pigmented villonodular synovitis, synovial chondromatosis.


Bone Tumor Synovial Sarcoma Fibrous Dysplasia Malignant Peripheral Nerve Sheath Tumor Giant Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 1999

Authors and Affiliations

  • Mario Campanacci
    • 1
    • 2
  1. 1.University of BolognaItaly
  2. 2.Rizzoli Orthopaedic InstituteBolognaItaly

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