Iron Overload

  • Manfred Wick
  • Paul Lehmann
  • Wulf Pinggera
Conference paper


The human body is incapable of actively excreting excess iron. An overabundant supply of iron leads to increased concentrations of the iron storage proteins ferritin and hemosiderin. If the storage capacity is exceeded, deposition takes place in the parenchymatous organs. The resulting cell damage leads to cell death and to functional impairment of the organ in question.


Iron Overload Human Leucocyte Antigen Hereditary Hemochromatosis Sideroblastic Anemia Plasma Ferritin 
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Copyright information

© Springer-Verlag Wien 2003

Authors and Affiliations

  • Manfred Wick
    • 1
  • Paul Lehmann
    • 2
  • Wulf Pinggera
    • 3
  1. 1.Institute of Clinical Chemistry, Klinikum GrosshadernUniversity of MunichGermany
  2. 2.Roche Diagnostics GmbHMannheimGermany
  3. 3.Medical DepartmentGeneral HospitalAmstettenAustria

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