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Abstract

The human body is incapable of actively excreting excess iron. An overabundant supply of iron leads to increased concentrations of the iron storage proteins ferritin and hemosiderin. If the storage capacity is exceeded, deposition takes place in the parenchymatous organs. The resulting cell damage leads to cell death and to functional impairment of the organ in question.

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© 2003 Springer-Verlag Wien

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Wick, M., Lehmann, P., Pinggera, W. (2003). Iron Overload. In: Clinical Aspects and Laboratory Iron Metabolism, Anemias. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3719-2_9

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  • DOI: https://doi.org/10.1007/978-3-7091-3719-2_9

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-00695-5

  • Online ISBN: 978-3-7091-3719-2

  • eBook Packages: Springer Book Archive

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