The human body is incapable of actively excreting excess iron. An overabundant supply of iron leads to increased concentrations of the iron storage proteins ferritin and hemosiderin. If the storage capacity is exceeded, deposition takes place in the parenchymatous organs. The resulting cell damage leads to cell death and to functional impairment of the organ in question.
KeywordsIron Overload Human Leucocyte Antigen Hereditary Hemochromatosis Sideroblastic Anemia Plasma Ferritin
Unable to display preview. Download preview PDF.