Doxorubicin liposomal

  • Ines Mader
  • Patrizia E. Fürst-Weger
  • Robert M. Mader
  • Elisabeth I. Semenitz
  • Robert Terkola
  • Sabine M. Wassertheurer


Dermal Toxicity Conventional Doxorubicin Topical Cool Documentation Sheet Extravasation Injury 
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Original articles

  1. [1]
    Forssen EA, Tökeé ZA: Attenuation of dermal toxicity of doxorubicin by liposome encapsulation. Cancer Treat Rep 67: 481–484, 1983.PubMedGoogle Scholar
  2. [2]
    Madhavan S, Northfelt DW: Lack of vesicant injury following extravasation of liposomal doxorubicin. J Natl Cancer Inst 87: 1556–1557, 1995.PubMedCrossRefGoogle Scholar
  3. [3]
    Balazsovits JA, Mayer LD, Bally MB, et al: Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumor efficacy of doxorubicin. Cancer Chemother Pharmacol 23: 81–86, 1989.PubMedCrossRefGoogle Scholar
  4. [4]
    Schmidmair M: personal communication, May 1999.Google Scholar

Secondary literature

  1. [5]
    van Gemmern R: Gewebstoxizität and Paravasatbehandlung neuer Zytostatika. Krankenhauspharmazie 17: 471–473, 1996.Google Scholar
  2. [6]
    Dezube BJ: Safety assessment: Doxil® (doxorubicin HC1 liposome injection) in refractory AIDS-related Kaposi’s sarcoma. Doxil Clinical Series 1: 1–7, 1997.Google Scholar
  3. [7]
    Mullin S, Beckwith MC, Tyler LS: Prevention and management of antineoplastic extravasation injury. Hosp Pharm 35: 57–76, 2000.Google Scholar
  4. [8]
    Dorr RT: Antidotes to vesicant chemotherapy extravasations. Blood Rev 4: 41–60, 1990.PubMedCrossRefGoogle Scholar
  5. [9]
    Bertelli G: Prevention and management of extravasation of cytotoxic drugs. Drug Safety 12: 245–255, 1995.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Wien 2003

Authors and Affiliations

  • Ines Mader
    • 1
  • Patrizia E. Fürst-Weger
    • 2
  • Robert M. Mader
    • 3
  • Elisabeth I. Semenitz
    • 4
  • Robert Terkola
    • 5
  • Sabine M. Wassertheurer
    • 6
  1. 1.Austrian Breast and Colorectal Cancer Study GroupViennaAustria
  2. 2.SMZ FloridsdorfKrankenhaus und GeriatriezentrumViennaAustria
  3. 3.Clinical Division of Oncology, Department of Medicine IUniversity HospitalViennaAustria
  4. 4.AnstaltsapothekeLandeskrankenhaus — Universitätskliniken InnsbruckAustria
  5. 5.Kaiser-Franz-Josef HospitalViennaAustria
  6. 6.Apotheke LKH-Univ.-Klinikum GrazAustria

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