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F-18-FDG PET in Oncology

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Abstract

An unstable, neutron-poor, atomic nucleus usually decays by emitting a positron. The emitted positron is the antiparticle of the electron, that means it has the same weight as the electron, but is conversely charged. This positive particle travels a short distance within the surrounding matter. On its way through the matter, the positron loses almost the whole amount of its kinetic energy and recombines with an electron. The masses of both particles are converted into energy in accordance with Einstein’s law of energy conservation. To conserve energy and linear momentum, the resulting electromagnetic radiation is in the form of two gamma-photons of 511 keV and emitted in opposite directions. This process is called annihilation and leads to a divergent emission of the two equal energy photons. The distance a positron covers before annihilation depends on the kind of isotope used (see Table 1).

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Lind, P., Unterweger, O. (2001). F-18-FDG PET in Oncology. In: Hruby, W. (eds) Digital (R)Evolution in Radiology. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3707-9_27

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