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P System

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Human Blood Groups

Abstract

The first antigen of the blood group P system, P 1 , was discovered in 1927 by Landsteiner and Levine [51]; the system was expanded in 1935 when the antigens P [82] and P k [44,45,65] were discovered and shown to be part of the P system. Five blood group P phenotypes can be defined according to the presence or absence of these three serological specificities on the erythrocytes, two of which, P 1 , and P 2 , are frequent and three, P 1 k, P 2 k, and p, very rare (Tab. 8.1) [81]:

  • P 1 , erythrocytes are characterised by the presence of P 1 , and P antigen

  • P 2 cells lack the P antigen

  • in P 1 k and P 2 k erythrocytes the P determinant is absent and the cells show strong P k activity; the presence of P 1 antigen distinguishes the P 1 k phenotype from P 2 k,

  • none of the three antigenic characters are detectable on p cells (see Tab. 8.2).

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  1. Institut für Biochemie, Universität Wien, Vienna, Austria

    Dr. Helmut Schenkel-Brunner

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© 1995 Springer-Verlag Wien

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Schenkel-Brunner, H. (1995). P System. In: Human Blood Groups. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3686-7_8

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  • DOI: https://doi.org/10.1007/978-3-7091-3686-7_8

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