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Rh System

  • Helmut Schenkel-Brunner

Abstract

In 1939, Levine and Stetson [64] first assumed that serological incompatibility between mother and child was the cause of erythroblastosis foetalis, or haemolytic disease of the newborn (HDN). The authors found that a maternal antibody entering the foetal circulation leads to destruction of foetal erythrocytes. One year later, Wiener and Peters [113] were able to identify the same antibody in the serum of individuals showing transfusion reactions after ABO-compatible blood transfusions. In 1941, Levine et al. [65] reported that the antibody responsible for this disease had the same specificity as the anti-Rhesus antibody obtained by Landsteiner and Wiener [59,60] after injecting rabbits and guinea pigs with erythrocytes of rhesus monkeys.

Keywords

Blood Group Erythrocyte Membrane Human Erythrocyte Membrane Blood Group System Human Blood Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Wien 1995

Authors and Affiliations

  • Helmut Schenkel-Brunner
    • 1
  1. 1.Institut für BiochemieUniversität WienViennaAustria

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