Other Drugs Used in Neuroanaesthesia

  • Jörn Bo Madsen
  • Georg Emil Cold


In monkeys, intravenous infusion of lidocaine in subconvulsive doses is associated with diffuse slowing of the EEG activity, and accordingly lidocaine has anticonvulsive properties in experimental epilepsy. On the other hand, lidocaine might elicit epileptic seizures and an arterial threshold concentration has been defined. Like central analgesics, inhalation anaesthetics and hypnotics, lidocaine decreases the utilization of acetylcholine in the brain (Ngai et al. 1979).


Intracranial Hypertension Blood Viscosity Cerebral Autoregulation Osmotic Gradient Oncotic Pressure 
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Copyright information

© Springer-Verlag Wien 1990

Authors and Affiliations

  • Jörn Bo Madsen
    • 1
  • Georg Emil Cold
    • 2
  1. 1.Department of AnaesthesiologyCopenhagen County Hospital at HvidovreHvidovreDenmark
  2. 2.Department of NeuroanaesthesiologyÅrhus KommunehospitalÅrhusDenmark

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