Other Drugs Used in Neuroanaesthesia
In monkeys, intravenous infusion of lidocaine in subconvulsive doses is associated with diffuse slowing of the EEG activity, and accordingly lidocaine has anticonvulsive properties in experimental epilepsy. On the other hand, lidocaine might elicit epileptic seizures and an arterial threshold concentration has been defined. Like central analgesics, inhalation anaesthetics and hypnotics, lidocaine decreases the utilization of acetylcholine in the brain (Ngai et al. 1979).
KeywordsIntracranial Hypertension Blood Viscosity Cerebral Autoregulation Osmotic Gradient Oncotic Pressure
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