Morphology of white matter, subcortical, dementia in Alzheimer’s disease

  • A. Brun
  • L. Gustafson
  • E. Englund
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Dementing disorders are not only caused by grey matter alterations but also by white matter lesions, either together with grey matter changes or as the sole change. In dementia of Alzheimer’s type white matter disease in the nature of a selective incomplete white matter infarction was found in around 60% of cases. It was regarded as being most likely due to regional hypoperfusion of the white matter and might therefore be prevented, halted or even partly reversed by therapy.


White Matter White Matter Lesion White Matter Change Senile Dementia Normal Pressure Hydrocephalus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 1990

Authors and Affiliations

  • A. Brun
    • 1
  • L. Gustafson
    • 2
  • E. Englund
    • 1
  1. 1.Institute of Pathology, Department of NeuropathologyUniversity HospitalLundSweden
  2. 2.Department of PsychogeriatricsUniversity HospitalLundSweden

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