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High resolution regional cerebral blood flow measurements in Alzheimer’s disease and other dementia disorders

  • J. Risberg
  • L. Gustafson
  • A. Brun
Part of the Key Topics in Brain Research book series (KEYTOPICS)

Summary

High-resolution regional cerebral blood flow (rCBF) measurements using inhalation of 133xenon and a newly developed 254 detector system were performed in patients with organic dementia. Neuropathological findings were compared to rCBF in 13 deceased patients. A close relationship was found between the localization and severety of atrophy and/or infarcts situated in the cortical mantle and the rCBF-findings. Pathological changes in subcortical regions and white matter showed a less clear relationship to rCBF. The rCBF technique was found to be a useful diagnostic tool.

Keywords

Regional Cerebral Blood Flow Frontal Flow Inhalation Technique Neuropathological Finding Cortical Mantle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Wien 1990

Authors and Affiliations

  • J. Risberg
    • 1
  • L. Gustafson
    • 2
  • A. Brun
    • 3
  1. 1.Departments of PsychiatryUniversity HospitalLundSweden
  2. 2.PsychogeriatricsUniversity HospitalLundSweden
  3. 3.Institute of Pathology, Department of NeuropathologyUniversity HospitalLundSweden

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