Oxygen metabolism in the degenerative dementias

  • P. J. Tyrrell
  • M. N. Rossor
  • R. S. J. Frackowiak
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Positron Emission Tomography (PET) is a quantitative technique which can be used to measure regional values of cerebral metabolism in the living human at rest. While structural scans (CT or MRI) may be normal in the degenerative dementias, or show generalised atrophy, functional imaging techniques allow differentiation of subtypes of dementias according to patterns of dysmetabolism. This paper describes some of the variety of alterations in patterns of oxygen metabolism that may be observed in degenerative cognitive disorders, and their correlations with clinical subtypes.


Positron Emission Tomography Oxygen Metabolism Posterior Cortical Atrophy Degenerative Dementia Alzheimer Type Dementia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 1990

Authors and Affiliations

  • P. J. Tyrrell
    • 1
    • 2
    • 3
  • M. N. Rossor
    • 2
    • 3
  • R. S. J. Frackowiak
    • 1
    • 2
  1. 1.MRC Cyclotron UnitHammersmith HospitalUK
  2. 2.National Hospital for Nervous DiseaseUK
  3. 3.St Mary’s HospitalLondonUK

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