Results of EEG brain mapping and neuroimaging methods in Senile Dementia of Alzheimer’s Typ (SDAT) and Vascular Dementia (VD)
In order to determine the impact of neuroimaging methods and EEG brain mapping on the differential diagnosis of dementia 11 patients with SDAT and 11 patients with VD were studied. All SDAT patients scored 2 or less on the Rosen-Hackinski scale, the vascular dementia patients 4 or more. The Mini Mental and Mattis scale scores were similar. MRI showed cerebral infarcts in 82% of the VD group versus 0% in the SDAT group. Basal ganglia hyperintensities in early confluent and confluent white matter lesions occurred more frequently in the VD group SPECT revealed cortical minor perfusions mainly in patients with VD, diffuse frontal and diffuse parietal temporal cortical minor perfusions were detected exclusively in patients with SDAT. Duplex scanning of the carotid arteries showed no significant difference of the status of the extracranial carotid arteries between the 2 dementia groups.
EEG brain mapping clearly demonstrate the slowing down of the basis rhythm in the SDAT patients, the main advantage in comparison with routine EEG lies in the statistical possibilities of this method.
It could be shown that the use of neuroimaging methods and EEG brain mapping adds significantly to the capability of clinical scores to differentiate between degenerative and vascular etiology of dementia, improving the possibilities of treatment and prevention.
KeywordsVascular Dementia Duplex Scanning Dementia Group Neuroimaging Method Basis Rhythm
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- Van der Drift JH, Kok NK (1972) The EEG in cerebrovascular disorders in relation to pathology. In: Remond A (ed) Handbook of EEG and clinical neurophysiology, vol 14, part A. Elsevier, Amsterdam, pp 12–64Google Scholar
- Lechner H, Niederkorn K, Logar C, Schmidt R, Fazekas F (1990) EEG brain mapping in patients with SDAT and vascular dementia — results and correlations with MRI, SPECT and TCD. In: Battistin L (ed) Aging brain and dementia: new trends in diagnosis and therapy. Alan R Liss, New York, pp 337–348Google Scholar
- Meyer JS, Lechner H, Marshall J, Toole JF (eds) (1988) Vascular and multi-infarct dementia. Futura Publishing Co, Mount Kisco, NYGoogle Scholar
- Meyer JS, Lechner H, Reivich M, Toole JF (eds) (1989) Cerebral vascular diseases, 7. Excerpta Medica, Amsterdam New York OxfordGoogle Scholar
- Obrist WD (1978) Electroencephalography in aging and dementia. In: Katzman R, Terry RD, Blick KL (eds) Alzheimer’s disease: senile dementia and related disorders. Raven Press, New York (Aging, vo1 7 )Google Scholar