Diagnostic criteria of Alzheimer’s disease

  • L. Gustafson
  • A. Brun
  • A. Johansson
  • J. Risberg
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Alzheimer’s disease (AD) with presenile onset is characterized by a consistent pattern of cognitive, emotional and neurological symptoms, in accordance with the accentuated degeneration of temporo-parietal and temporal limbic grey matter. The clinical picture is influenced by the age at onset and the duration of the disease and may be confounded by co-existent white matter changes. Differentiation between AD, vascular dementia and dementia with fronto-temporal degeneration of non-Alzheimer type, is possible by the use of clinical methods, e.g. special rating scales, which are described and validated.


Vascular Dementia Regional Cerebral Blood Flow Memory Failure Presenile Dementia Ischemic Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 1990

Authors and Affiliations

  • L. Gustafson
    • 1
  • A. Brun
    • 2
  • A. Johansson
    • 1
  • J. Risberg
    • 3
  1. 1.Department of Psychogeriatrics, Department of NeuropathologyUniversity of LundSweden
  2. 2.Department of Institute of Pathology, Department of NeuropathologyUniversity of LundSweden
  3. 3.Department of Psychiatry, Department of NeuropathologyUniversity of LundSweden

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