Periventricular Infarcts

  • Reinhard L. Friede


Parrot (1868 a) gave a short but precise description of periventricular infarcts which he called “cerebral steatose” attributing them to malnutrition. A second paper (1868 b) contains a convincing illustration. He mentions the presence of cerebral steatose in several later articles dealing with other disease entities in infants. Parrot (1873) recognized the periventricular lesions as initial phases of “pale infarcts”, distinguishing them from the red softenings caused by phlebothrombosis. He also emphasized that periventricular infarcts differed, in principle, from the diffuse fatty change described by Virchow (1867). Virchow (1867, 1868) is widely misquoted as being the first to describe periventricular infarcts. He really described diffuse fatty changes in the white matter of the brain and spinal cord (Chapter 5), although mentioning briefly that fatty cells may accumulate in certain places to the extent that they become recognizable to the naked eye. Sixteen years later Virchow (1883) distinguished diffuse fatty change from a focal form leading to softening; yet, he never detailed the appearance or distribution of these lesions, considering them merely a local intensification of diffuse fatty change.


White Matter Lateral Ventricle Residual Lesion Periventricular Leukomalacia Lateral Corner 


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Copyright information

© Springer-Verlag Wien 1975

Authors and Affiliations

  • Reinhard L. Friede
    • 1
    • 2
  1. 1.Case Western Reserve UniversityClevelandUSA
  2. 2.University of ZurichSwitzerland

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