Skip to main content

Disturbances in the Bulk Growth of Nervous Tissue

  • Chapter
Book cover Developmental Neuropathology

Abstract

Diseases affecting the bulk growth of the nervous system may be negative, resulting in a deficit in the formation of neural parenchyma, that is micrencephaly, or positive, resulting in a surplus, or megalencephaly.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Altman, J., Anderson, W. J., Wright, K. A.: Differential radiosensitivity of stationary and migratory primitive cells in the brains of infant rats. Exp. Neurol. 22: 52–74, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Apley, J., Symons, M.: Megalencephaly: a report of 2 cases. Arch. Dis. Child. 22: 172–174, 1947.

    Article  PubMed  CAS  Google Scholar 

  • Bannayan, G. A.: Lipomatosis, angiomatosis and macrencephalia. Arch. Path. 92: 1–5, 1971.

    PubMed  CAS  Google Scholar 

  • Bass, N. H., Netsky, M. G., Young, E.: Effect of neonatal malnutrition on developing cerebrum. I. Microchemical and histologic study of cellular differentiation in the rat. Arch. Neurol. (Chic.) 23: 289–302, 1970.

    Article  CAS  Google Scholar 

  • Bass, N. H., Netsky, M. G., Young, E.: Effect of neonatal malnutrition on developing cerebrum. II. Microchemical and histologic study of myelin formation in the rat. Arch. Neurol. (Chic.) 23: 303–313, 1970.

    Article  CAS  Google Scholar 

  • Bignami, A., Palladini, G., Zappella, M.: Unilateral megalencephaly with nerve cell hypertrophy. An anatomical and quantitative histochemical study. Brain Res. 9: 103–114, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Blinkov, S. M., Glezer, I. I.: The Human Brain in Figures and Tables. A Quantitative Handbook. New York: Plenum Press 1968.

    Google Scholar 

  • Blot, W. L., Miller, R. W.: Mental retardation following in utero exposure to the atomic bombs of Hiroshima and Nagasaki. Radiology 106: 617–620, 1973.

    PubMed  CAS  Google Scholar 

  • Böök, J. A., Schut, J. W., Reed, S. C.: A clinical and genetical study of microcephaly. Amer. J. ment. Defic. 57: 637–660, 1953.

    PubMed  Google Scholar 

  • Brown, R. E.: Decreased brain weight in malnutrition and its implications. E. Afr. med. J. 42: 584–595, 1965.

    CAS  Google Scholar 

  • Davies, H., Kirman, B.: Microcephaly. Arch. Dis. Child. 37: 623–627, 1962.

    Article  PubMed  CAS  Google Scholar 

  • Davis, R. L., Nelson, E.: Unilateral ganglioglioma in a tuberosclerotic brain. J. Neuropath. exp. Neurol. 20: 571–581, 1961.

    Article  PubMed  CAS  Google Scholar 

  • de Lange, C.: Über Megalencephalie. Acta Psychiat. Neurol. 7: 955–980, 1932.

    Google Scholar 

  • De Myer, W.: Megalencephaly in children. Clinical syndromes, genetic patterns, and differential diagnosis from other causes of megalocephaly. Neurology (Minneap.) 22: 634–643, 1972.

    Article  Google Scholar 

  • Dennis, J. P., Rosenberg, H. S., Alvord, E. C., Jr.: Megalencephaly, internal hydrocephalus and other neurological aspects of achondroplasia. Brain 84: 427–445, 1961.

    Article  PubMed  CAS  Google Scholar 

  • Diamond, M. C., Johnson, R. E., Ingham, C., Stone, B.: Lack of direct effect of hypophysectomy and growth hormone on postnatal rat brain morphology. Exp. Neurol. 23: 51–57, 1969.

    Article  PubMed  CAS  Google Scholar 

  • Dobbing, J., Hopewell, J. W., Lynch, A., Sands, J.: Vulnerability of developing brain: I. Some lasting effects of X-irradiation. Exp. Neurol. 28: 442–449, 1970.

    Article  PubMed  CAS  Google Scholar 

  • Dobbing, J., Sands, J.: Vulnerability of developing brain. IX. The effect of nutritional growth retardation on the timing of the brain growth-spurt. Biol. Neonat. 19: 363–378, 1971.

    Article  CAS  Google Scholar 

  • Dom, R., Brucher, J. M.: Hamartoblastome (gangliocytome diffus) unilatéral de l’écorce cérébrale. Rev. Neurol. 120: 307–318, 1969.

    PubMed  CAS  Google Scholar 

  • Dyggve, H., Tygstrup, I.: Megalencephaly. Develop. Med. Child. Neurol. 6: 581–584, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Escourolle, R., Poirier, J.: Manual of Basic Neuropathology (Rubinstein, L. J., translator). Philadelphia: Saunders 1973.

    Google Scholar 

  • Fletcher, H. M.: A case of megalencephaly. Path. Soc. London 51: 230–232, 1900.

    Google Scholar 

  • Giacomini, C.: Contributo allo studio della microcefalia. Arch. Psych. (Torino) 6: 63–81, 1885.

    Google Scholar 

  • Goldstein, L.: Radiogenic microcephaly. Arch. Neurol. Psychiat. 24: 102–115, 1930.

    Google Scholar 

  • Gregory, K. M., Diamond, M. C.: Effects of early hypophysectomy on brain morphogenesis in the rat. Exp. Neurol. 20: 394–402, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Gross, H., Uiberrak, B.: Klinisch-anatomische Befunde bei Hemimegalencephalie. Virchows Arch. path. Anat. 327: 577–589, 1955.

    CAS  Google Scholar 

  • Hallervorden, J.: Angeborene Hemihypertrophie der linken Körperhälfte einschließlich des Gehirns. Zbl. Neurol. Psychiat. 33: 518–519, 1923.

    Google Scholar 

  • Hanhart, E.: Über einfache Rezessivität bei Mikrocephalia vera, spuria et combinata. Acta Genet. Med. (Roma) 7: 445–520, 1958.

    CAS  Google Scholar 

  • Hicks, S. P.: Developmental malformations produced by radiation: a time table of their development. Amer. J. Roentgenol. 69: 272–293, 1953.

    PubMed  CAS  Google Scholar 

  • Hicks, S. P.: Mechanism of radiation anencephaly, anophthalmia and pituitary anomalies. Arch. Path. 57: 363–378, 1954.

    CAS  Google Scholar 

  • Howard, E.: Reductions in size and total DNA of cerebrum and cerebellum in adult mice after corticosterone treatment in infancy. Exp. Neurol. 22: 191–208, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Jacob, H.: Eine Gruppe familiärer Micro- und Mikrencephalie. Z. ges. Neurol. Psychiat. 156: 633–645, 1936.

    Article  Google Scholar 

  • Jakob, A.: Anatomie und Histologie des Großhirns. Leipzig-Wien: Franz Deuticke 1927.

    Google Scholar 

  • Kloepfer, H. W., Platou, R. V., Hanschew, J.: Manifestation of recessive gene for microcephaly in a population isolate. J. Génét. hum. 13: 52–59, 1964.

    PubMed  CAS  Google Scholar 

  • Koch, G.: Genetics of microcephaly in man. Acta Genet. Med. (Roma) 8: 75–85, 1959.

    CAS  Google Scholar 

  • Komai, T., Kishimoto, K., Ozaki, Y.: Genetic study of microcephaly based on Japanese material. Amer. J. hum. Genet. 7: 51–65, 1955.

    PubMed  CAS  Google Scholar 

  • Langman, J., Shimada, M.: Cerebral cortex of the mouse after prenatal chemical insult. Amer. J. Anat. 132: 355–374, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Laurence, K. M.: A case of unilateral megalencephaly. Develop. Med. Child. Neurol. 6: 585–590, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Matsumoto, H., Spatz, M., Laqueur, G. L.: Quantitative changes with age in the DNA content of methylazoxymethanol-induced microencephalic rat brain. J. Neurochem. 19: 297–306, 1972.

    Article  PubMed  CAS  Google Scholar 

  • Minkowski, M.: Sur les altérations de l’écorce cérébrale dans quelques cas de microcéphalie. Schweiz. Arch. Neurol. Psychiat. 76: 110–173, 1955.

    CAS  Google Scholar 

  • Monakow, C. v.: Biologisches und Morphogenetisches über die Mikrocephalia vera. Schweiz. Arch. Neurol. Psychiat. 12: 1–39, 1926.

    Google Scholar 

  • Neville, H. E., Chase, H. P.: Undernutrition and cerebellar development. Exp. Neurol. 33: 485–497, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Norman, R. M.: Malformations of the nervous system, birth injury and diseases of early life. I. Prenatal malformations. In: Greenfield’s Neuropathology, Chapter 6, pp. 324–440. London: Arnold 1969.

    Google Scholar 

  • Pearl, T.: Biometrical studies in man. Variation and correlation in brain weights. Biometrica 4: 13–104, 1905.

    Google Scholar 

  • Peter, K., Schluter, K.: Über Megalencephalie als Grundlage der Idiotie. Z. ges. Neurol. Psychiat. 108: 21–40, 1927.

    Article  Google Scholar 

  • Pfaffenroth, M. J., Das, G. D., McAllister, J. P.: Teratologic effects of ethylnitrosourea on brain development in rats. Teratology 9: 305–316, 1974.

    Article  PubMed  CAS  Google Scholar 

  • Polan, D., Butterworth, T.: Cutis verticis gyrata. Amer. J. ment. Defic. 57: 613–631, 1953.

    PubMed  CAS  Google Scholar 

  • Robain, O., Lyon, G.: Les micrencéphalies familiales par malformation cérébrale. Etude anatomoclinique. Acta neuropath. (Berl.) 20: 96–109, 1972.

    CAS  Google Scholar 

  • Rugel, S. J.: Congenital hemihypertrophy. Amer. J. Dis. Child. 71: 530–536, 1946.

    CAS  Google Scholar 

  • Schelling-Dürst, V.: Makrozephaler Großwuchs. Klin. Pädiat. 186: 97–106, 1974.

    Google Scholar 

  • Spatz, M., Laqueur, G. L.: Transplacental chemical induction of microencephaly in two strains of rats. I. (34404). Soc. exp. Biol. Med. 129: 705–710, 1968.

    CAS  Google Scholar 

  • Stephenson, J. N., Mellinger, R. C., Manson, M.: Cerebral gigantism. Pediatrics 41: 130–138, 1968.

    PubMed  CAS  Google Scholar 

  • Sylvester, P. E.: Cerebral atrophy in microcephalic cousins. Arch. Dis. Child. 34: 325–330, 1959.

    Article  PubMed  CAS  Google Scholar 

  • Townsend, J. J., Nielsen, S. L., Malamud, N.: Unilateral megalencephaly: hamartoma or neoplasm. Neurology 25: 448–453, 1975.

    Article  PubMed  CAS  Google Scholar 

  • Ward, J., Lerner, H. H.: Review of subject of congenital hemihypertrophy and complete case report. J. Pediat. 31: 403–414, 1947.

    Article  PubMed  CAS  Google Scholar 

  • Webster, J. H. D.: A case of unilateral cerebral hyperplasia, which coexists with “acromegaly” of the feet, and a slight degree of unilateral gigantism. J. Path. Bact. 12: 306–321, 1908.

    Article  Google Scholar 

  • Wegner, G., Mecking, H.: Autoradiographische Untersuchungen der DNS-Neubildung in Gehirnanlagen nach einmaliger Röntgenbestrahlung später Embryonal- und Fetalstadien der Ratte. Z. ges. exp. Med. 149: 2–12, 1969.

    CAS  Google Scholar 

  • Wilson, K. A. S.: Megalencephaly. J. Neurol. Psychopath. 14: 193–216, 1934.

    Article  CAS  Google Scholar 

  • Winick, M., Fish, I., Ross, P.: Cellular recovery in rat tissues after a brief period of neonatal malnutrition. J. Nutr. 95: 623–626, 1968.

    PubMed  CAS  Google Scholar 

  • Wood, J. W., Johnson, K. G., Omori, Y.: In utero exposure to the Hiroshima atomic bomb. Pediatrics 39: 385–392, 1967.

    PubMed  CAS  Google Scholar 

  • Zamenhof, Z., Mosley, J., Schuller, E.: Stimulation of the proliferation of cortical neurons by prenatal treatment with growth hormone. Science 152: 1396–1397, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Zamenhof, Z., van Marthens, E., Grauel, L.: DNA (cell number) in neonatal brain: Second generation (F2) alteration by maternal (Fo) dietary protein restriction. Science 172: 850–850, 1971.

    Article  PubMed  CAS  Google Scholar 

  • Zamenhof, Z., van Marthens, E., Margolis, F. L.: DNA (cell number) and protein in neonatal brain: Alteration by maternal dietary protein restriction. Science 160: 322–323, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Zappert, J.: Über röntgenogene foetale Mikrozephalie. Arch. Kinderheilk. 80: 34–50, 1926.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1975 Springer-Verlag Wien

About this chapter

Cite this chapter

Friede, R.L. (1975). Disturbances in the Bulk Growth of Nervous Tissue. In: Developmental Neuropathology. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3338-5_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-3338-5_27

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-3340-8

  • Online ISBN: 978-3-7091-3338-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics