Zusammenfassung
L-3,4-Dihydroxyphenylalanin (L-Dopa, Levodopa), eine neutrale L-Arninosäure, ist die unmittelbare metabolische Vorstufe der Katecholamine Dopamin, L-Noradrenalin und L-Adrenalin, dreier biogener Amine mit wichtigen physiologischen Funktionen als Hormone und Neurotransmitter. L-Dopa wurde erstmals um das Jahr 1900 in Studien über Adrenalin erwähnt. Seine Rolle als Zwischenprodukt der Dopamin-Biosynthese wurde nach und nach erkannt (Tabelle 3.1) (Sourkes und Gauthier 1983).
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Colzi, A., Zürcher, G., Kettler, R., Da Prada, M., Schneider, E. (1992). L-Dopa. In: Riederer, P., Laux, G., Pöldinger, W. (eds) Neuro-Psychopharmaka. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3330-9_3
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