Zusammenfassung
Co-Dergocrin-Mesilat ist ein Mutterkornalkaloid, das im Verhältnis 3:3:2:1 aus den Methansulfonaten der vier dehydrierten Ergopeptidderivate: Dihydrocornin, Dihy-droergocristin, Dihydro-Alpha-ergocryptin, Dihydro-Beta-ergocryptin zusammengesetzt ist. Co-Dergocrin zeigt, wie die meisten Mutterkornalkaloide, ein breites Spektrum pharmakologischer Wirkungen, die nicht auf einen einzigen grundlegenden Mechanismus auf zellulärer oder molekularer Ebene zurückzuführen sind. Co-Dergocrin besitzt wie die Einzelkomponenten eine blockierende Wirkung auf Alpha-Adrenorezeptoren.
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Herrschaft, H. (1992). Co-Dergocrin (Dihydroergotoxin). In: Riederer, P., Laux, G., Pöldinger, W. (eds) Neuro-Psychopharmaka. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3330-9_15
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