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Abstract

The term “flavin” stands for the yellow redox-active subgroup of the first coenzyme ever to be elucidated in terms of molecular structure. The “heroic” period of redox-enzymology of the early thirties ended in Hugo Theroell’s (172175) description of the first enzyme ever to be split reversibly to yield coenzyme and apoprotein. This was the NADPH-oxidizing “Old Yellow Enzyme” from yeast, whose biological function is still unknown even nowadays. The structure of the coenzyme has been shown to be riboflavin-5’-phosphate, viz. a phosphate derivative of vitamin B2, which had been synthesized somewhat earlier by Karrer’s group (83), who based this work upon even more important chemical precursor studies of Kuhn and coworkers (102, 100) and on the biochemical work of Warburg and Christian (188).

Keywords

Succinate Dehydrogenase Pulse Radiolysis Electron Transfer Flavoprotein Violuric Acid Flavin Radical 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Wien 1976

Authors and Affiliations

  • P. Hemmerich
    • 1
  1. 1.Fachbereich BiologieUniversität KonstanzFederal Republic of Germany

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