Oxidative Cyclization Stannic Chloride Allylic Alcohol Geranyl Acetate Diphenyl Phosphate 


Efforts directed toward the synthesis of naturally occurring cornpounds have, almost from the inception of this kind of work followed two kinds of pathways. The first and for many years the major road travelled was that of total synthesis. Thus the steady accretion of knowlege concerning the structural and stereochemical course of such reactions as base catalyzed condensation, enolate alkylation, and catalytic hydrogenation resulted in the years following the second world war in a series of elegant syntheses of such complex molecules as strychnine, cortisone, chlorophyl, cevine, longifoline, onocerin, germanicol, etc. The alternative approach less well explored until recent years has been the path of biogenetic-type synthesis.


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© Springer-Verlag Wien 1971

Authors and Affiliations

  • D. Goldsmith
    • 1
  1. 1.AtlantaUSA

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