Intracranial Saccular Aneurysms

  • J. D. Humphrey
Part of the International Centre for Mechanical Sciences book series (CISM, volume 441)


It has long been accepted that mechanical factors play a critical role in the natural history of intracranial saccular aneurysms — their pathogenesis, enlargement, and rupture. Nevertheless, until very recently, biomechanical analysis has been surprisingly scant. In this chapter, we see how nonlinear elasticity, membrane theory, nonlinear dynamics, and nonlinear finite element analyses can be used to increase our understanding of the mechanics of saccular aneurysms. Much has been learned, but much remains to be accomplished, particularly in the area of the mechanics of biological growth and remodeling. Hence, it is also hoped that this chapter will encourage new investigators to study the mechanics of aneurysms.


Constitutive Relation Principal Curvature Stretch Ratio Saccular Aneurysm Membrane Theory 
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Copyright information

© Springer-Verlag Wien 2003

Authors and Affiliations

  • J. D. Humphrey
    • 1
  1. 1.Biomedical EngineeringTexas A&M UniversityCollege StationUSA

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