Element of Physiology and Mechanics of Human Arteries

  • Robert S. Reneman
  • Arnold P. G. Hoeks
  • Lilian Kornet
Part of the International Centre for Mechanical Sciences book series (CISM, volume 446)

Abstract

Some elements concerning the physiology and the corresponding mechanical properties of human arteries are introduced. The non-invasive ultrasound techniques developed to assess strain, distensibility and compliance and IMT, velocity and wall shear rate/stress distribution in arteries are introduced. Artery wall properties, and intima-media thickness (IMT) change with age and disease are discussed with the relation with artery wall function and structure and role in the genesis of atherosclerosis. In hypertension and with aging elastic arteries become stiffer (loss of distensibility and compliance), the degree of stiffening also varies along artery bifurcations and differs in elastic and muscular arteries. These variations give differences in intima-media thickness and sites of preference for atherosclerosis. Alterations in structure and composition of the arterial wall responsible for the loss of distensibility and compliance and the increase in intima-media thickness (IMT) in disease and aging. Reasons and effects are discussed.

Keywords

Wall Shear Stress Pulse Wave Velocity Artery Wall Superficial Femoral Artery Sample Window 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Wien 2003

Authors and Affiliations

  • Robert S. Reneman
    • 1
  • Arnold P. G. Hoeks
    • 1
  • Lilian Kornet
    • 1
  1. 1.Departments of Physiology and Biophysics, Cardiovascular Research InstituteMaastricht UniversityMaastrichtThe Netherlands

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