Tryptophan Accumulation by Blood Platelets of Depressed Patients

  • K. Wood
  • C. Swade
  • A. Coppen
Conference paper
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 15)


The accumulation of tryptophan by blood platelets has been investigated in depressive patients and controls using short incubation times and low substrate concentrations. The accumulation of tryptophan by the platelet is significantly greater in the acutely depressed patients than the control group. The results are discussed with reference to tryptophan transport in depression and also to the regulation of plasma levels of tryptophan.


Depressed Patient Blood Platelet Depressive Illness Short Incubation Time Neural Transmission 
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Copyright information

© Springer-Verlag Wien 1979

Authors and Affiliations

  • K. Wood
    • 1
  • C. Swade
    • 1
  • A. Coppen
    • 1
  1. 1.MRC Neuropsychiatry LaboratoryWest Park HospitalEpsom, SurreyUK

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