Abstract
In addition to fluid and lipid absorption, immune cell trafficking has now become recognized as one of the major functions of the lymphatic system. Recently, several critical roles of the lymphatic vessels (LVs) in modulating immune reactions during both physiological and pathological conditions have been emerging. As LVs serve as conduits for immune cells, they come to closely interact with macrophages/monocytes, dendritic cells, and T and B lymphocytes. Accumulating evidences indicate that reciprocal interactions between the LVs and immune cells exist which cause considerable influence over the process of immune cell migration, LV growth, and ultimately certain immune reactions. This chapter discusses on the interactions of macrophages/monocytes and dendritic cells with peripheral LVs and on those of sinusoidal macrophages and T and B lymphocytes with lymph node LVs.
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Acknowledgments
This work was supported by the grant (R2009-0079390 and 2011-0019268, GYK) of the National Research Foundation (NRF) funded by the MEST, Korea. We apologize to the many authors whose important work could not be cited because of space restrictions. The author has no conflicting financial interest.
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Kataru, R.P., Lee, Y.G., Koh, G.Y. (2014). Interactions of Immune Cells and Lymphatic Vessels. In: Kiefer, F., Schulte-Merker, S. (eds) Developmental Aspects of the Lymphatic Vascular System. Advances in Anatomy, Embryology and Cell Biology, vol 214. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1646-3_9
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DOI: https://doi.org/10.1007/978-3-7091-1646-3_9
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