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Sleep Disordered Breathing in Parkinson’s Disease

  • Michael K. ScullinEmail author
  • Lynn Marie Trotti
  • Donald L. Bliwise
Chapter
  • 996 Downloads

Abstract

Sleep disordered breathing (SDB) is a serious medical condition in which there are repeated reductions or cessations of breathing during sleep. Early research suggested that because Parkinson’s disease (PD) patients have pulmonary abnormalities while they are awake they may be at increased risk for developing sleep disordered breathing. A large literature now demonstrates that sleep disordered breathing is common in Parkinson’s disease patients, but no different than age-matched controls from the general population. In the general population, sleep disordered breathing often correlates with excessive daytime sleepiness, but this correlation is not typically observed within Parkinson’s disease patients. However, sleep disordered breathing in Parkinson’s disease has been preliminarily linked to impaired sleep-dependent memory consolidation, blunted sympathetic responses, and worsening motor function Unified Parkinson’s Disease Rating Scale (UPDRS). Parkinson’s disease patients who have sleep disordered breathing may benefit from positive airway pressure or mandibular advancement treatments, and an exciting avenue for future research is determining whether such treatment also positively affects disease progression and quality of life.

Keywords

Obstructive Sleep Apnea Obstructive Sleep Apnea Syndrome Sleep Disorder Breathing Excessive Daytime Sleepiness Berlin Questionnaire 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

Preparation of this chapter was supported by funding from the National Institute on Health (grant numbers 1P50NS071669 and F32AG041543). M.K.S. was partially supported by an Emory University School of Medicine Cottrell Fellowship.

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Copyright information

© Springer-Verlag Wien 2015

Authors and Affiliations

  • Michael K. Scullin
    • 1
    Email author
  • Lynn Marie Trotti
    • 2
  • Donald L. Bliwise
    • 2
  1. 1.Department of Psychology and NeuroscienceBaylor UniversityWacoUSA
  2. 2.Department of NeurologyEmory University School of MedicineAtlantaUSA

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