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The Non-motor Parkinson’s Disease

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Movement Disorders Curricula

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Abstract

Parkinson’s disease (PD) is the second commonest neurodegenerative condition, and non-motor symptoms (NMS) are integral to the condition [62]. Besides the common visible motor symptoms such as tremor, rigidity and bradykinesia, patients experience NMS thorough the course of the disease including the prodromal and palliative phase of PD. For some time now, evidence has shown that PD has a multiple neurotransmitters deficiency involving the central and the extra central nervous system. Recently the concept of NMS subtypes has emerged with potential subtype specific treatment options in the future.

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Acknowledgements

EUROPAR and IPMDS non-motor study group for data collection of studies reported. This paper presents independent research funded by the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust and King’s College London. We acknowledge the help and support of the international Parkinson’s non-motor group and in particular Professor Pablo Martinez-Martin and his team in the Institute of Neuroepidemiology, Madrid, for co-leading all studies related to NMSQuest and NMSS described in this paper.

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Authors and Affiliations

  1. National Parkinson Foundation International Centre of Excellence, King’s College Hospital NHS Foundation Trust, 9th Floor Ruskin Wing, Denmark Hill, London, SE5 9RS, UK

    Anna Sauerbier, L. Klingelhoefer, M. A. Qamar, H. Carr & K. Ray Chaudhuri

  2. King’s College London, London, UK

    Anna Sauerbier, L. Klingelhoefer, M. A. Qamar, H. Carr & K. Ray Chaudhuri

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  1. Anna Sauerbier
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  2. L. Klingelhoefer
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  3. M. A. Qamar
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  4. H. Carr
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  5. K. Ray Chaudhuri
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Correspondence to Anna Sauerbier .

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Editors and Affiliations

  1. Faculty of Medicine, Transilvania University, Brasov, Romania

    Cristian Falup-Pecurariu

  2. Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Lisbon, Portugal

    Joaquim Ferreira

  3. National Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain

    Pablo Martinez-Martin

  4. Centre of Excellence, King’s College London, National Parkinson Foundation Centre of Excellence King’s College, London, United Kingdom

    Kallol Ray Chaudhuri

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Sauerbier, A., Klingelhoefer, L., Qamar, M.A., Carr, H., Ray Chaudhuri, K. (2017). The Non-motor Parkinson’s Disease. In: Falup-Pecurariu, C., Ferreira, J., Martinez-Martin, P., Chaudhuri, K. (eds) Movement Disorders Curricula. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1628-9_12

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