Abstract
The occurrence of gouty tophi is typical for the chronic stage of gouty arthritis. Tophaceous gout of the spine is rare. It is caused by the deposits of natrium urate crystals into the intervertebral space, intervertebral joints, and fibrous tissue, and it forms epidural masses. This paper presents an overview of published rare cases of sine syndrome in gout – evidence of tophi in the spine in patients previously not treated for gout – without prior documented hyperuricemia, arthritis attacks or tophi in other locations. In these cases, where there is no history of chronic gouty arthritis in a patient with back pain and neurological symptoms, diagnosis is difficult. Computed tomography and magnetic resonance imaging are helpful in the diagnosis, but a definitive diagnosis was established by the histopathological analysis of the material obtained by decompressive laminectomy or needle biopsy.
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Rovenský, J., Sedláková, J. (2014). Tophaceous Gout in the Spine Without Prior Hyperuricemia or Tophi in Other Locations. In: Rovenský, J., Herold, M., Vašáková, M. (eds) Sine Syndromes in Rheumatology. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1541-1_14
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DOI: https://doi.org/10.1007/978-3-7091-1541-1_14
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