Abstract
Stereotactic radiosurgery (SRS) works by applying highly localized, focused radiation to a pathological target. It produces cure by damaging the target with the high dose and sparing adjacent tissues by a rapid dose falloff outside the target. The targets should not be large. It follows that a well-defined lesion with a clear-cut margin is the ideal target. This being so, apart from cerebral metastases, most malignancies would seem to be unsuitable for the method. They have unclear margins as a consequence of invading surrounding normal tissue. Also, they have been seen to be resistant to conventional radiotherapy. Moreover, many of them are larger than ideal for SRS.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
McCutcheon IE (2013) Stereotactic radiosurgery for malignant extracerebral intracranial tumors: patient selection, efficacy, and technical nuances. Acta Neurochir Suppl 116:71–83 (present volume)
Mori Y, Tsugawa T, Hashizume C, Kobayashi T, Shibamoto Y (2013) Gamma knife stereotactic radiosurgery for atypical and malignant meningiomas. Acta Neurochir Suppl 116:85–89 (present volume)
Takakura K, Hayashi M, Chernov MF, Tamura N, Izawa M, Okada Y, Tamura M, Muragaki Y, Iseki H (2013) Gamma knife treatment strategy for metastatic brain tumors. Acta Neurochir Suppl 116:63–69 (present volume)
Conflict of Interest
The author works as a consultant for Elekta AB Company, which manufactures the Gamma Knife. He has received no financial support in the preparation of this Editorial and can state that there is no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag Wien
About this paper
Cite this paper
Ganz, J.C. (2013). Role of Radiosurgery in the Management of Intracranial Malignancies. In: Chernov, M., Hayashi, M., Ganz, J., Takakura, K. (eds) Gamma Knife Neurosurgery in the Management of Intracranial Disorders. Acta Neurochirurgica Supplement, vol 116. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1376-9_10
Download citation
DOI: https://doi.org/10.1007/978-3-7091-1376-9_10
Published:
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-1375-2
Online ISBN: 978-3-7091-1376-9
eBook Packages: MedicineMedicine (R0)