Epidermolysis Bullosa (EB) — The Condition

Abstract

‘Bulla (lat.) f: Blister; primary skin eruption; a cavity filled with liquid raised above the normal skin level; caused by a simple separation between the layers of the skin, usually only one chamber; at least 5 mm; differentiation is made between the localisation and the cause: subcorneal bulla (below the cornea), intra-epidermal bulla (in the epidermis), sub-epidermal bulla (between the epidermis and the corium) and acantholytic bulla (in the epidermis due to the breakup of the cell structures); bulla inflammatoris (inflammatory blister due to toxic noxa, inflammatory, allergic reactions, etc.), bulla mechanica (due to mechanical injury in epidermolysis), bulla actinica (due to exposure to the sun, e. g. hydroa vacciniforme), bulla spontanea (e. g. pemphigoid). Compare with efflorescence’ (Pschyrembel 2012, p. 328).