Abstract
Background: Only a few experimental reports are available on the direct comparison of Licox® and Raumedic®-Neurovent-PTO brain tissue oxygen pressure (PbrO2) monitors. We compared the two systems regarding their measurement properties under experimental in vitro and in vivo conditions.
Materials and methods: Eight Licox® and Raumedic® Neurovent-PTO® sensors were tested for 10 min at 37°C, atmospheric pressure, at an oxygen content of 0% and 100% before and after the in vivo test. The same probes were implanted in German landrace pigs, which underwent hepatectomy. The mean PbrO2 values were recorded every minute. An O2 challenge with inhalation of 100% O2 for 10 min was performed 2 h post-abdominal surgery.
Results: At 0% O2 content values varied from 0.2 to 7 mmHg, at 100% O2 content from 130 to 165 mmHg. No difference between probes was found. In vivo tests: Raumedic® showed higher PbrO2 values (mean +6.3 mmHg, p < 0.0001) compared with Licox®. During O2 challenge, both probes responded similarly; however, Raumedic® had a 10% higher response amplitude (p < 0.005). After explantation there was again no difference between the two sensors.
Conclusion: Raumedic® sensors measured higher PbrO2 values. There was no significant difference regarding overall measurement of in vitro accuracy between the two probes, which proved to be robust when used consecutively for longer periods and in different environments.
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Conflict of interest statement
Martin U. Schuhmann has received a research grant from Raumedic AG for the implementation of multimodal monitoring in animal research.
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Morgalla, M.H. et al. (2012). Experimental Comparison of the Measurement Accuracy of the Licox® and Raumedic® Neurovent–PTO Brain Tissue Oxygen Monitors. In: Schuhmann, M., Czosnyka, M. (eds) Intracranial Pressure and Brain Monitoring XIV. Acta Neurochirurgica Supplementum, vol 114. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0956-4_32
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DOI: https://doi.org/10.1007/978-3-7091-0956-4_32
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