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Immune Recognition of Parasite Glycans

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Anticarbohydrate Antibodies

Abstract

Glycan antigens have a long and detailed history in parasite immunology, dating back to identification of an allergenic polysaccharide from the nematode roundworm Ascaris by Campbell in 1936 (Campbell 1936). In the intervening 75 years, an extraordinary array of carbohydrate structures have emerged from both of the major biological groups of parasite, the unicellular protozoa and the multicellular (metazoan) helminth worms. Parasite glycans are represented in a full range of carrier molecules, including glycoproteins through O- and N-linkages, unusual glycolipid structures, and polysaccharides.

A chapter contributed to:

Anticarbohydrate Antibodies – from Molecular Basis to Clinical Applications

Editor : Paul Kosma; Pub : Springer New York Vienna, 2011

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  1. Institute of Immunology and Infection Research, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, UK

    Rick M. Maizels & James P. Hewitson

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  1. Rick M. Maizels
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  2. James P. Hewitson
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Correspondence to Rick M. Maizels .

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  1. , Department für Chemie, Universität für Bodenkultur Wien, Muthgasse 18, Wien, 1190, Austria

    Paul Kosma

  2. , Zentrum für Medizin und Biowissenschafte, Forschungszentrum Borstel, Parkallee 22, Borstel, 23845, Germany

    Sven Müller-Loennies

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Maizels, R.M., Hewitson, J.P. (2012). Immune Recognition of Parasite Glycans. In: Kosma, P., Müller-Loennies, S. (eds) Anticarbohydrate Antibodies. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0870-3_7

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