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Resting-state brain networks in functional Magnetic Resonance Imaging (MRI)

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Brain Mapping

Abstract

Blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has been extensively used to study how task performance modulates brain activity. Such an approach emphasizes the principle of functional segregation, in that different brain areas are characterized by their involvement in specific cognitive processes. However, this type of analysis essentially ignores that the brain maintains a constant level of spontaneous activity, i.e., activity that is not a direct consequence of environmental stimulations. Investigating these spontaneous brain fluctuations is a challenge precisely because they cannot be controlled by an experimental design. The first successful study of brain spontaneous fluctuations by BOLD fMRI was performed by Biswal and colleagues [3], who computed the correlation between the time course of a seed region and all brain voxels in the absence of any experimental task.

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Authors
  1. Pierre Bellec
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  2. Arnaud Messé
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  3. David Coynel
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  4. Vincent Perlbarg
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  5. Habib Benali
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  6. Guillaume Marrelec
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Hôital Gui de Chauliac CHU Montpellier, Montpellier, France

    Hugues Duffau MD, PhD

  2. Institute of Neuroscience of Montpellier INSERM U1051, Plasticity of Central Nervous System, Human Stem Cells and Glial Tumors, Hôital Saint Eloi CHU Montpellier, Montpellier, France

    Hugues Duffau MD, PhD

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© 2011 Springer-Verlag/Wien

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Bellec, P., Messé, A., Coynel, D., Perlbarg, V., Benali, H., Marrelec, G. (2011). Resting-state brain networks in functional Magnetic Resonance Imaging (MRI). In: Duffau, H. (eds) Brain Mapping. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0723-2_28

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  • DOI: https://doi.org/10.1007/978-3-7091-0723-2_28

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-0722-5

  • Online ISBN: 978-3-7091-0723-2

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