Abstract
Writing a chapter on one particular treatment for the condition known as trigeminal neuralgia is one of the more daunting tasks for the author of a book such as this. There are few conditions for which there are so many different treatment options and so much disagreement amongst experts as to the optimal treatment and treatment sequence in a given case. As is usual in such situations, this disagreement reflects the complexity of the condition and its frequent resistance to treatment. Thus, because of this complexity more detail than usual of the various areas of knowledge and ignorance, of theory and practice need to be outlined if the reader is to be able to find his/her way through the labyrinth of available information. Let us begin with a consideration of the definition of this clinical condition, where the diagnosis is almost wholly dependent on what the patient says. The definitions below are quoted from the “Headache Classification Subcommittee of the International Headache Society: The International classification and diagnostic criteria for headache disorders, cranial neuralgia and facial pain. Ed 2” [1]. The first unquestionable description of the disease is attributed to Nicolaus André in 1756 [2]. He coined the phrase “tic douloureux” to describe the muscular twitches associated with the lightning like attacks of pain.
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Notes
- 1.
There is evidence from Pittsburgh that ultra thorough clinical examination and neurophysiological examinations can demonstrate consistent abnormalities in these patients, despite the above definition [3].
References
Headache Classification Subcommittee of the International Headache Society: The International classification and diagnostic criteria for headache disorders, cranial neuralgia and facial pain. Ed 2 Cephalalgia 24 Suppl 1: 9–160; 2004
Eboli P, Stone JL, Aydin S, Slavin KV. Historical characterization of trigeminal neuralgia. Neurosurgery 64(6): 1183–1187; 2009
Rand RW, Jacques DB, Melbye RW, Copcutt BG, Levenick MN, Fisher MR. Leksell gamma knife treatment of tic douloureux. Stereotact Funct Neurosurg 61(Suppl 1): 93–102; 1992
Kerr FW. Evidence for a peripheral etiology of trigeminal neuralgia. J Neurosurg 26(1 Suppl): 168–174; 1967
Kerr FW. Pathology of trigeminal neuralgia: light and electron microscopic observations. J Neurosurg 26(1 Suppl): 151–156; 1967
Love S, Coakham HB. Trigeminal neuralgia. Pathology and pathogenesis. Brain 124(12): 2347–2360; 2001
Malis LI. Petrous ridge compression and its surgical correction. J Neurosurg 26(1 Suppl): 163–167; 1967
Jannetta PJ. Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia. J Neurosurg 26(1 Suppl): 159–162; 1967
Jannetta PJ. Trigeminal neuralgia. Neurosurg Focus 18(5): Intro; 2005
Jannetta PJ, McLaughlin MR, Casey KF. Technique of microvascular decompression. Technical note. Neurosurg Focus 18(5): E5; 2005
King RB. Evidence for a central etiology of tic douloureux. J Neurosurg 26(1 Suppl): 175–180; 1967
Sweet WH, Poletti CE, Macon JB. Treatment of trigeminal neuralgia and other facial pains by retrogasserian injection of glycerol. Neurosurgery 9(6): 647–653; 1981
Adams CB. Microvascular compression: an alternative view and hypothesis. J Neurosurg 70(1): 1–12; 1989
Dandy WE. The treatment of trigeminal neuralgia by the cerebellar route. Ann Surg 96: 787–795; 1932
Adams CB, Kaye AH, Teddy PJ. The treatment of trigeminal neuralgia by posterior fossa microsurgery. J Neurol Neurosurg Psychiatry 45(11): 1020–1026; 1982
Janetta PJ. Treatment of Trigeminal Neuralgia by Micro-operative decompression ed 3. Saunders, Philadelphia; 1990
Linskey ME, Ratanatharathorn V, Penagaricano J. A prospective cohort study of microvascular decompression and Gamma Knife surgery in patients with trigeminal neuralgia. J Neurosurg 109(Suppl): 160–172; 2008
Casey KF. Role of patient history and physical examination in the diagnosis of trigeminal neuralgia. Neurosurg Focus 18(5): E1; 2005
Brisman R, Khandji AG, Mooij RB. Trigeminal nerve-blood vessel relationship as revealed by high-resolution magnetic resonance imaging and its effect on pain relief after gamma knife radiosurgery for trigeminal neuralgia. Neurosurgery 50(6): 1261–1266; 2002
Cohen DB, Oh MY, Jannetta PJ. Trigeminal neuralgia: surgical perspective. in (eds) Chin LS, Regine WF. Principles and Practice of Stereotactic Radiosurgery. Springer Science+ Business Media LLC, New York: pp 527–534; 2008
Klun B. Microvascular decompression and partial sensory rhizotomy in the treatment of trigeminal neuralgia: personal experience with 220 patients. Neurosurgery 30(1): 49–52; 1992
Møller AR, Heros RC, Apfelbaum RI, Aoki N, Ambrosetto P, Silbergeld D. Views on microvascular compression: to the editor. J Neurosurg 71(3): 459–464; 1989
Jawahar A, Kondziolka D, Kanal E, Bissonette DJ, Lunsford LD. Imaging the trigeminal nerve and pons before and after surgical intervention for trigeminal neuralgia. Neurosurgery 48(1): 101–106; 2001
Campos-Benitez M, Kaufmann AM. Neurovascular compression findings in hemifacial spasm. J Neurosurg 109(3): 416–420; 2008
Pollock BE, Ecker RD. A prospective cost-effectiveness study of trigeminal neuralgia surgery. Clin J Pain 21(4): 317–322; 2005
Masur H, Papke K, Bongartz G, Vollbrecht K. The significance of three-dimensional MR-defined neurovascular compression for the pathogenesis of trigeminal neuralgia. J Neurol 242(2): 93–98; 1995
Sheehan JP, Ray DK, Monteith S, Yen CP, Lesnick J, Kersh R, Schlesinger D. Gamma knife radiosurgery for trigeminal neuralgia: the impact of magnetic resonance imaging-detected vascular impingement of the affected nerve. J Neurosurg 113: 53–58; 2010
Lorenzoni J, David P, Devriendt D, Desmedt F, De WO, Massager N. Patterns of neurovascular compression in patients with classic trigeminal neuralgia: a high-resolution MRI-based study Eur J Radiol: 2010 [Epub ahead of print]
Burchiel KJ, Clarke H, Haglund M, Loeser JD. Long-term efficacy of microvascular decompression in trigeminal neuralgia. J Neurosurg 69(1): 35–38; 1988
Kolluri S, Heros RC. Microvascular decompression for trigeminal neuralgia. A five-year follow-up study. Surg Neurol 22(3): 235–240; 1984
Blom S. Trigeminal neuralgia: its treatment with a new anticonvulsant drug (G-32883). Lancet 1(7234): 839–840; 1962
Parker NC. Trigeminal neuralgia: medical management perspective. in (eds) Chin LS, Regine WF. Principles and Practice of Stereotactic Radiosurgery. Springer Science+Business Media LLC, New York: pp 535–540; 2008
Dalessio DJ. Trigeminal neuralgia. A practical approach to treatment. Drugs 24(3): 248–255; 1982
Horsley V, Taylor J, Colman WS. Remarks on the various surgical procedures devised for the relief of trigeminal neuralgia (tic douloureux). Br Med J 2: 1249–1252; 1891
Speller WG, Frazier WG. The division of the sensory root of the trigeminus for the relief of tic douloureux; an experimental, pathological and clinical study with a preliminary report of one surgically successful case. The Philadelphia Medical Journal 8: 1039–1049; 1901
Cushing H. A method of total extirpation of the Gasserian ganglion for trigeminal neuralgia. By a route through the temporal fossa and beneath the middle meningeal artery. J. Am Med Ass 34: 1035–1041: 1900
Taarnhøj P. Decompression of the trigeminal root and the posterior part of the ganglion as treatment in trigeminal neuralgia. Preliminary communication. J Neurosurg 9(3): 288–290; 1952
Taarnhøj P. Decompression of the posterior trigeminal root in trigeminal neuralgia. A 30-year follow-up review. J Neurosurg 57(1): 14–17; 1982
Lopez BC, Hamlyn PJ, Zakrzewska JM. Systematic review of ablative neurosurgical techniques for the treatment of trigeminal neuralgia. Neurosurgery 54(4): 973–982; 2004
Rogers CL, Shetter AG, Fiedler JA, Smith KA, Han PP, Speiser BL. Gamma knife radiosurgery for trigeminal neuralgia: the initial experience of The Barrow Neurological Institute. Int J Radiat Oncol Biol Phys 47(4): 1013–1019; 2000
Theodosopoulos PV, Marco E, Applebury C, Lamborn KR, Wilson CB. Predictive model for pain recurrence after posterior fossa surgery for trigeminal neuralgia. Arch Neurol 59(8): 1297–1302; 2002
Kondziolka D, Zorro O, Lobato-Polo J, Kano H, Flannery TJ, Flickinger JC, Lunsford LD. Gamma Knife stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg 112(4): 758–765; 2010
McNatt SA, Yu C, Giannotta SL, Zee CS, Apuzzo ML, Petrovich Z. Gamma knife radiosurgery for trigeminal neuralgia. Neurosurgery 56(6): 1295–1301; 2005
Pollock BE Comparison of posterior fossa exploration and stereotactic radiosurgery in patients with previously nonsurgically treated idiopathic trigeminal neuralgia. Neurosurg Focus 18(5): E6; 2005
Régis J, Metellus P, Hayashi M, Roussel P, Donnet A, Bille-Turc F. Prospective controlled trial of gamma knife surgery for essential trigeminal neuralgia. J Neurosurg 104(6): 913–924; 2006
Barker FG 2nd, Jannetta PJ, Bissonette DJ, Larkins MV, Jho HD. The long-term outcome of microvascular decompression for trigeminal neuralgia. N Engl J Med 334(17): 1077–1083; 1996
Fardy MJ, Zakrzewska JM, Patton DW. Peripheral surgical techniques for the management of trigeminal neuralgia – alcohol and glycerol injections. Acta Neurochir 129(3–4): 181–184; 1994
Loew F. Peripheral surgical techniques for the management of trigeminal neuralgia--alcohol and glycerol injections – editorial comments. Acta Neurochir 129(3–4): 185; 1994
Sweet WH, Wepsic JG. Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction of pain fibers. 1. Trigeminal neuralgia. J Neurosurg 40(2): 143–156; 1974
Broggi G, Franzini A, Lasio G, Giorgi C, Servello D. Long-term results of percutaneous retrogasserian thermorhizotomy for “essential” trigeminal neuralgia: considerations in 1000 consecutive patients. Neurosurgery 26(5): 783–786; 1990
Håkanson S. Trigeminal neuralgia treated by the injection of glycerol into the trigeminal cistern. Neurosurgery 9(6): 638–646; 1981
Leksell L. Sterotaxic radiosurgery in trigeminal neuralgia. Acta Chir Scand 137(4): 311–314; 1971
Fujimaki T, Fukushima T, Miyazaki S. Percutaneous retrogasserian glycerol injection in the management of trigeminal neuralgia: long-term follow-up results. J Neurosurg 73(2): 212–216; 1990
Burchiel KJ. Percutaneous retrogasserian glycerol rhizolysis in the management of trigeminal neuralgia. J Neurosurg 69(3): 361–366; 1988
Slettebø H, Hirschberg H, Lindegaard KF. Long-term results after percutaneous retrogasserian glycerol rhizotomy in patients with trigeminal neuralgia. Acta Neurochir 122(3–4): 231–235; 1993
Lunsford LD, Bennett MH. Percutaneous retrogasserian glycerol rhizotomy for tic douloureux: part 1. Technique and results in 112 patients. Neurosurgery 14(4): 424–430; 1984
Saini SS. Reterogasserian anhydrous glycerol injection therapy in trigeminal neuralgia: observations in 552 patients. J Neurol Neurosurg Psychiatry 50(11): 1536–1538; 1987
Mullan S, Lichtor T. Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. J Neurosurg 59(6): 1007–1012; 1983
Shelden CH, Pudenz RH, Freshwater DB, Crue BL. Compression rather than decompression for trigeminal neuralgia. J Neurosurg 12(2): 123–126; 1955
Brown JA, McDaniel MD, Weaver MT. Percutaneous trigeminal nerve compression for treatment of trigeminal neuralgia: results in 50 patients. Neurosurgery 32(4): 570–573; 1993
Skirving DJ, Dan NG. A 20-year review of percutaneous balloon compression of the trigeminal ganglion. J Neurosurg 94(6): 913–917; 2001
Kondziolka D, Lacomis D, Niranjan A, Mori Y, Maesawa S, Fellows W, Lunsford LD. Histological effects of trigeminal nerve radiosurgery in a primate model: implications for trigeminal neuralgia radiosurgery. Neurosurgery 46(4): 971–976; 2000
Foy AB, Parisi JE, Pollock BE. Histologic analysis of a human trigeminal nerve after failed stereotactic radiosurgery: case report. Surg Neurol 68: 655–658; 2007
Szeifert G, Salmon I, Lorenzoni J, Massager N, Levivier M. Pathological findings following trigeminal neuralgia radiosurgery. in (eds) Szeifert GT, Kondziolka D, Levivier M, Lunsford LD. Basel, Karger. Prog Neurol Surg 20: pp 244–248; 2007
Leksell L. Trigeminus neuralgi – Några neurofysiologiska aspekter och en ny behandlings metod. Läkartidningen 68(45): 5145–5148; 1971
Lindquist C, Kihlström L, Hellstrand E. Functional neurosurgery – a future for the gamma knife? Stereotact Funct Neurosurg 57: 72–81; 1991
Kondziolka D, Lunsford LD, Flickinger JC, Young RF, Vermeulen S, Duma CM, Jacques DB, Rand RW, Régis J, Peragut JC, Manera L, Epstein MH, Lindquist C. Stereotactic radiosurgery for trigeminal neuralgia: a multiinstitutional study using the gamma unit. J Neurosurg 84(6): 940–945; 1996
Cheuk AV, Chin LS, Petit JH, Herman JM, Fang HB, Regine WF. Gamma knife surgery for trigeminal neuralgia: outcome, imaging, and brainstem correlates. Int J Radiat Oncol Biol Phys 60(2): 537–541; 2004
Massager N, Abeloos L, Devriendt D, Op de Beeck M, Levivier M. Clinical evaluation of targeting accuracy of gamma knife radiosurgery in trigeminal neuralgia. Int J Radiat Oncol Biol Phys 69(5): 1514–1520; 2007
Erbay SH, Bhadelia RA, Riesenburger R, Gupta P, O'Callaghan M, Yun E, Oljeski S. Association between neurovascular contact on MRI and response to gamma knife radiosurgery in trigeminal neuralgia. Neuroradiology 48(1): 26–30; 2006
Zerris VA, Noren GC, Shucart WA, Rogg J, Friehs GM. Targeting the cranial nerve: microradiosurgery for trigeminal neuralgia with CISS and 3D-flash MR imaging sequences. J Neurosurg 102(Suppl): 107–110; 2005
Erbay SH, Bhadela RA, O'Callaghan M, Gupta P, Riesenburger R, Krackov W, Polak JF. Nerve atrophy in severe trigeminal neuralgia: noninvasive confirmation at MR imaging – initial experience. Radiology 238(2): 689–692; 2006
Lorenzoni JG, Massager N, David P, Devriendt D, Desmedt F, Brotchi J, Levivier M. Neurovascular compression anatomy and pain outcome in patients with classic trigeminal neuralgia treated by radiosurgery. Neurosurgery 62(2): 368–375; 2008
Dellaretti M, Reyns N, Touzet G, Sarrazin T, Dubois F, Lartigau E, Blond S. Clinical outcomes after gamma knife surgery for idiopathic trigeminal neuralgia: review of 76 consecutive cases. J Neurosurg 109(Suppl): 173–178; 2008
Dvorak T, Finn A, Price LL, Mignano JE, Fitzek MM, Wu JK, Yao KC. Retreatment of trigeminal neuralgia with gamma knife radiosurgery: is there an appropriate cumulative dose? Clinical article. J Neurosurg 111(2): 359–364; 2009
Hasegawa T, Kondziolka D, Spiro R, Flickinger JC, Lunsford LD. Repeat radiosurgery for refractory trigeminal neuralgia. Neurosurgery 50(3): 494–500; 2002
Huang CF, Chuang JC, Tu HT, Chou MC. Microsurgical outcomes after failed repeated gamma knife surgery for refractory trigeminal neuralgia. J Neurosurg 105(Suppl): 117–119; 2006
Huang CF, Chuang JC, Tu HT, Lin LY. Repeated gamma knife surgery for refractory trigeminal neuralgia. J Neurosurg 105(Suppl): 99–102; 2006
Massager N, Lorenzoni J, Devriendt D, Desmedt F, Brotchi J, Levivier M. Gamma knife surgery for idiopathic trigeminal neuralgia performed using a far-anterior cisternal target and a high dose of radiation. J Neurosurg 100(4): 597–605; 2004
Massager N, Murata N, Tamura M, Devriendt D, Levivier M, Régis J. Influence of nerve radiation dose in the incidence of trigeminal dysfunction after trigeminal neuralgia radiosurgery. Neurosurgery 60(4): 681–687; 2007
Massager N, Nissim O, Murata N, Devriendt D, Desmedt F, Vanderlinden B, Régis J, Levivier M. Effect of beam channel plugging on the outcome of gamma knife radiosurgery for trigeminal neuralgia. Int J Radiat Oncol Biol Phys 65(4): 1200–1205; 2006
Pollock BE, Phuong LK, Gorman DA, Foote RL, Stafford SL. Stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg 97(2): 347–353; 2002
Régis J, Arkha Y, Yomo S, Murata N, Roussel P, Donnet A, Peragut JC. Radiosurgery in trigeminal neuralgia: Long-term results and influence of operative nuances. Neurochirurgie 55(2): 213–222; 2009
Régis J, Metellus P, Dufour H, Roche PH, Muracciole X, Pellet W, Grisoli F, Peragut JC. Long-term outcome after gamma knife surgery for secondary trigeminal neuralgia. J Neurosurg 95(2): 199–205; 2001
Zheng LG, Xu DS, Kang CS, Zhang ZY, Li YH, Zhang YP, Liu D, Jia Q. Stereotactic radiosurgery for primary trigeminal neuralgia using the Leksell Gamma unit. Stereotact Funct Neurosurg 76(1): 29–35; 2001
Balamucki CJ, Stieber VW, Ellis TL, Tatter SB, Deguzman AF, McMullen KP, Lovat OJ, Shaw EG, Ekstrand KE, Bourland JD, Munley MT, Robbins M, Branch C. Does dose rate affect efficacy? The outcomes of 256 gamma knife surgery procedures for trigeminal neuralgia and other types of facial pain as they relate to the half-life of cobalt. J Neurosurg 105(5): 730–735; 2006
Brisman R. Gamma knife radiosurgery for primary management for trigeminal neuralgia. J Neurosurg 93(Suppl 3): 159–161; 2000
Brisman R. Gamma knife surgery with a dose of 75 to 76.8 Gray for trigeminal neuralgia. J Neurosurg 100(5): 848–854; 2004
Brisman R, Mooij R. Gamma knife radiosurgery for trigeminal neuralgia: dose-volume histograms of the brainstem and trigeminal nerve. J Neurosurg 93(Suppl 3): 155–158; 2000
Dhople A, Kwok Y, Chin L, Shepard D, Slawson R, Amin P, Regine W. Efficacy and quality of life outcomes in patients with atypical trigeminal neuralgia treated with gamma-knife radiosurgery. Int J Radiat Oncol Biol Phys 69(2): 397–403; 2007
Dhople AA, Adams JR, Maggio WW, Naqvi SA, Regine WF, Kwok Y. Long-term outcomes of gamma knife radiosurgery for classic trigeminal neuralgia: implications of treatment and critical review of the literature. Clinical article. J Neurosurg 111(2): 351–358; 2009
Flickinger JC, Pollock BE, Kondziolka D, Phuong LK, Foote RL, Stafford SL, Lunsford LD. Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? A prospective double-blind, randomized study. Int J Radiat Oncol Biol Phys 51(2): 449–454; 2001
Gellner V, Kurschel S, Kreil W, Holl E, Ofner-Kopeinig P, Unger F. Recurrent trigeminal neuralgia: long-term outcome of repeat gamma knife radiosurgery. J Neurol Neurosurg Psychiatry 79(12): 1405–1407; 2008
Han JH, Kim DG, Chung HT, Paek SH, Kim YH, Kim CY, Kim JW, Kim YH, Jeong SS. Long-term outcome of gamma knife radiosurgery for treatment of typical trigeminal neuralgia. Int J Radiat Oncol Biol Phys 75(3): 822–827; 2009
Henson CF, Goldman HW, Rosenwasser RH, Downes MB, Bednarz G, Pequignot EC, Werner-Wasik M, Curran WJ, Andrews DW. Glycerol rhizotomy versus gamma knife radiosurgery for the treatment of trigeminal neuralgia: an analysis of patients treated at one institution. Int J Radiat Oncol Biol Phys 63(1): 82–90; 2005
Herman JM, Petit JH, Amin P, Kwok Y, Dutta PR, Chin LS. Repeat gamma knife radiosurgery for refractory or recurrent trigeminal neuralgia: treatment outcomes and quality-of-life assessment. Int J Radiat Oncol Biol Phys 59(1): 112–116; 2004
Huang CF, Tu HT, Liu WS, Chiou SY, Lin LY. Gamma knife surgery used as primary and repeated treatment for idiopathic trigeminal neuralgia. J Neurosurg 109(Suppl): 179–184; 2008
Jawahar A, Wadhwa R, Berk C, Caldito G, DeLaune A, Ampil F, Willis B, Smith D, Nanda A. Assessment of pain control, quality of life, and predictors of success after gamma knife surgery for the treatment of trigeminal neuralgia. Neurosurg Focus 18(5): E8; 2005
Kondziolka D, Lunsford LD, Flickinger JC. Stereotactic radiosurgery for the treatment of trigeminal neuralgia. Clin J Pain 18(1): 42–47; 2002
Kondziolka D, Perez B, Flickinger JC, Habeck M, Lunsford LD. Gamma knife radiosurgery for trigeminal neuralgia: results and expectations. Arch Neurol 55(12): 1524–1529; 1998
Little AS, Shetter AG, Shetter ME, Bay C, Rogers CL. Long-term pain response and quality of life in patients with typical trigeminal neuralgia treated with gamma knife stereotactic radiosurgery. Neurosurgery 63(5): 915–923; 2008
Little AS, Shetter AG, Shetter ME, Kakarla UK, Rogers CL. Salvage gamma knife stereotactic radiosurgery for surgically refractory trigeminal neuralgia. Int J Radiat Oncol Biol Phys 74(2): 522–527; 2009
Longhi M, Rizzo P, Nicolato A, Foroni R, Reggio M, Gerosa M. Gamma knife radiosurgery for trigeminal neuralgia: results and potentially predictive parameters – part I: idiopathic trigeminal neuralgia. Neurosurgery 61(6): 1254–1260; 2007
Maesawa S, Salame C, Flickinger JC, Pirris S, Kondziolka D, Lunsford LD. Clinical outcomes after stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg 94(1): 14–20; 2001
Morbidini-Gaffney S, Chung CT, Alpert TE, Newman N, Hahn SS, Shah H, Mitchell L, Bassano D, Darbar A, Bajwa SA, Hodge C. Doses greater than 85 Gy and two isocenters in Gamma Knife surgery for trigeminal neuralgia: updated results. J Neurosurg 105(Suppl): 107–111; 2006
Nicol B, Regine WF, Courtney C, Meigooni A, Sanders M, Young B. Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia. J Neurosurg 93(Suppl 3): 152–154; 2000
Petit JH, Herman JM, Nagda S, DiBiase SJ, Chin LS. Radiosurgical treatment of trigeminal neuralgia: evaluating quality of life and treatment outcomes. Int J Radiat Oncol Biol Phys 56(4): 1147–1153; 2003
Pollock BE, Foote RL, Link MJ, Stafford SL, Brown PD, Schomberg PJ. Repeat radiosurgery for idiopathic trigeminal neuralgia. Int J Radiat Oncol Biol Phys 61(1): 192–195; 2005
Pollock BE, Foote RL, Stafford SL, Link MJ, Gorman DA, Schomberg PJ. Results of repeated gamma knife radiosurgery for medically unresponsive trigeminal neuralgia. J Neurosurg 93(Suppl 3): 162–164; 2000
Pollock BE, Phuong LK, Foote RL, Stafford SL, Gorman DA. High-dose trigeminal neuralgia radiosurgery associated with increased risk of trigeminal nerve dysfunction. Neurosurgery 49(1): 58–62
Rogers CL, Shetter AG, Ponce FA, Fiedler JA, Smith KA, Speiser BL. Gamma knife radiosurgery for trigeminal neuralgia associated with multiple sclerosis. J Neurosurg 97(5 Suppl): 529–532; 2002
Urgosik D, Liscak R, Novotny J Jr, Vymazal J, Vladyka V. Treatment of essential trigeminal neuralgia with gamma knife surgery. J Neurosurg 102(Suppl): 29–33; 2005
Young RF, Vermulen S, Posewitz A. Gamma knife radiosurgery for the treatment of trigeminal neuralgia. Stereotact Funct Neurosurg 70(Suppl 1): 192–199; 1998
Matsuda S, Serizawa T, Nagano O, Ono J. Comparison of the results of 2 targeting methods in Gamma Knife surgery for trigeminal neuralgia. J Neurosurg 109(Suppl): 185–189; 2008
Alberico RA, Fenstermaker RA, Lobel J. Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. AJNR Am J Neuroradiol 22(10): 1944–1948; 2001
Alpert TE, Chung CT, Mitchell LT, Hodge CJ, Montgomery CT, Bogart JA, Kim DY, Bassano DA, Hahn SS. Gamma knife surgery for trigeminal neuralgia: improved initial response with two isocenters and increasing dose. J Neurosurg 102(Suppl): 185–188; 2005
Drzymala RE, Malyapa RS, Dowling JL, Rich KM, Simpson JR, Mansur DB. Gamma knife radiosurgery for trigeminal neuralgia: the Washington University initial experience. Stereotact Funct Neurosurg 83(4): 148–152; 2005
Fountas KN, Lee GP, Smith JR. Outcome of patients undergoing gamma knife stereotactic radiosurgery for medically refractory idiopathic trigeminal neuralgia: Medical College of Georgia’s experience. Stereotact Funct Neurosurg 84(2–3): 88–96; 2006
Friedman DP, Morales RE, Goldman HW. Role of enhanced MRI in the follow-up of patients with medically refractory trigeminal neuralgia undergoing stereotactic radiosurgery using the gamma knife: initial experience. J Comput Assist Tomogr 25(5): 727–732; 2001
Kanner AA, Neyman G, Suh JH, Weinhous MS, Lee SY, Barnett GH. Gamma knife radiosurgery for trigeminal neuralgia: comparing the use of a 4-mm versus concentric 4- and 8-mm collimators. Stereotact Funct Neurosurg 82(1): 49–57; 2004
Martinez-Moreno NE, Martinez-Alvarez R, Rey-Portoles G, Gutierrez-Sarraga J, Burzaco-Santurtun J, Bravo G. Gamma knife radiosurgery treatment of trigeminal neuralgia and atypical facial pain. Rev Neurol 42(4): 195–201; 2006
Matsuda S, Serizawa T, Sato M, Ono J. Gamma knife radiosurgery for trigeminal neuralgia: the dry-eye complication. J Neurosurg 97(5 Suppl): 525–528; 2002
Shaya M, Jawahar A, Caldito G, Sin A, Willis BK, Nanda A. Gamma knife radiosurgery for trigeminal neuralgia: a study of predictors of success, efficacy, safety, and outcome at LSUHSC. Surg Neurol 61(6): 529–534; 2004
Shetter AG. Trigeminal neuralgia: the impact of magnetic resonance imaging-detected vascular impingement of the affected ner, Zabramski JM, Speiser BL Microvascular decompression after gamma knife surgery for trigeminal neuralgia: intraoperative findings and treatment outcomes. J Neurosurg 102(Suppl): 259–261; 2005
Tawk RG, Duffy-Fronckowiak M, Scott BE, Alberico RA, Diaz AZ, Podgorsak MB, Plunkett RJ, Fenstermaker RA. Stereotactic gamma knife surgery for trigeminal neuralgia: detailed analysis of treatment response. J Neurosurg 102(3): 442–449; 2005
Young RF, Vermeulen SS, Grimm P, Blasko J, Posewitz A. Gamma knife radiosurgery for treatment of trigeminal neuralgia: idiopathic and tumor related. Neurology 48(3): 608–614; 1997
Zorro O, Lobato-Polo J, Kano H, Flickinger JC, Lunsford LD, Kondziolka D. Gamma knife radiosurgery for multiple sclerosis-related trigeminal neuralgia. Neurology 73(14): 1149–1154; 2009
Wang L, Zhao ZW, Qin HZ, Li WT, Zhang H, Zong JH, Deng JP, Gao GD. Repeat gamma knife radiosurgery for recurrent or refractory trigeminal neuralgia. Neurol India 56: 36–41; 2008
Brisman R. Microvascular decompression vs. gamma knife radiosurgery for typical trigeminal neuralgia: preliminary findings. Stereotact Funct Neurosurg 85(2–3): 94–98; 2006
Fountas KN, Smith JR, Lee GP, Jenkins PD, Cantrell RR, Sheils WC. Gamma knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications. Neurosurg Focus 23: E8; 2007
Sheehan J, Pan HC, Stroila M, Steiner L. Gamma knife surgery for trigeminal neuralgia: outcomesand prognostic factors. J Neurosurg 102(3): 431–444; 2005
Huang CF, Tu HT, Liu WS, Lin LY. Gamma knife surgery for trigeminal pain caused by benign brain tumors. J Neurosurg 109(Suppl): 154–159; 2008
Kang JH, Yoon YS, Kang DW, Chung SS, Chang JW. Gamma knife radiosurgery for medically refractory idiopathic trigeminal neuralgia. Acta Neurochir Suppl 101: 35–38; 2008
Brisman R. Repeat gamma knife radiosurgery for trigeminal neuralgia. Stereotact Funct Neurosurg 81(1–4): 43–49; 2003
Pollock BE. Radiosurgery for trigeminal neuralgia: is sensory disturbance required for pain relief? J Neurosurg 105(Suppl): 103–106; 2006
Chang JW, Chang JH, Park YG, Chung SS. Gamma knife radiosurgery for idiopathic and secondary trigeminal neuralgia. J Neurosurg 93(Suppl 3): 147–151; 2000
Régis J, Metellus P, Lazorthes Y, Porcheron D, Peragut JC. Effect of gamma knife on secondary trigeminal neuralgia. Stereotact Funct Neurosurg 70(Suppl 1): 210–217; 1998
Cheng JS, Sanchez-Mejia RO, Limbo, M, Ward MM, Barbaro NM. Management of medically refractory trigeminal neuralgia in patients with multiple sclerosis. Neurosurg Focus 18(5): E13; 2005
Miller JP, Acar F, Burchiel KJ. Trigeminal neuralgia and vascular compression in patients with trigeminal schwannomas: case report. Neurosurgery 62(4): E974–E975; 2008
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© 2011 Springer-Verlag/Wien
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Ganz, J.C. (2011). Trigeminal Neuralgia. In: Gamma Knife Neurosurgery. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0343-2_20
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DOI: https://doi.org/10.1007/978-3-7091-0343-2_20
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