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Part of the book series: Methods in Clinical Pharmacology ((MECLPH))

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Zusammenfassung

Beim Menschen und bei Nagern lassen sich signifikante Tageszeitabhängigkeiten in den verschiedensten Funktionen des kardiovaskulären Systems nachweisen. Wirkungen und Pharmakokinetik von antihypertensiv wirkenden Pharmaka wie β-, und α- und β-Adrenozeptorenblockern sind nicht unabhängig von den Tagesrhythmen in diesen physiologischen Funktionen. Human- und tierexperimentelle chronopharmakologische Untersuchungen können somit zum besseren Verständnis der Regulationsmechanismen des kardiovaskulären Systems aber auch zur Verbesserung der Therapie der Hypertonie beitragen.

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© 1984 Springer Fachmedien Wiesbaden

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Lemmer, B. (1984). Zur Chronopharmakologie von Adrenozeptorenblockem. In: Rietbrock, N., Woodcock, B.G. (eds) Balanced Alpha/Beta Blockade of Adrenoceptors / Balancierte Blockade von Alpha- und Beta-Adrenozeptoren. Methods in Clinical Pharmacology. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-20205-9_3

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  • DOI: https://doi.org/10.1007/978-3-663-20205-9_3

  • Publisher Name: Vieweg+Teubner Verlag, Wiesbaden

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