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Abstract

The metabolism and different accumulation of cholesterol esters, phospholipids and triglycerides in normal and atherosclerotic artery attract considerable interest for obvious reasons. However, relatively little attention has been paid so far to close interactions within and between the lipid classes and processes.

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References

  • Abdulla, Y. H., Orton, C. C., and Adams, C. W. M. (1968): Cholesterol esterification by transacylation in human and experimental atheromatous lesions. J. Atheroscler. Res. 8, 967.

    Article  PubMed  CAS  Google Scholar 

  • Howard, A. N., Gresham, G. A., Jones, D., and Jennings, I. W. (1965): The prevention of rabbit atherosclerosis by soya bean meal. J. Atheroscler. Res. 5, 330.

    Article  PubMed  CAS  Google Scholar 

  • Howard A. N., Patelski, J., Bowyer, D. E., and Gresham, G. A. (1971): Atherosclerosis induced in hypercholesterolaemic baboons by immunological injury; and the effects of intravenous polyunsaturated phosphatidyl choline. Atherosclerosis 14, 17–29.

    Article  PubMed  CAS  Google Scholar 

  • Howard, A. N., and Patelski, J. (1974): Hydrolysis and synthesis of aortic cholesterol esters in atherosclerotic baboons. Effect of polyunsaturated phosphatidyl choline on enzyme activities. Atherosclerosis 20, 225–232.

    Article  PubMed  CAS  Google Scholar 

  • Kritchevsky, D., Tepper, S. A., Genzano, J. C., and Kothari, H. V. (1974): Aortic cholesterol estrease in rabbits. Effect of duration of cholesterol feeding. Atherosclerosis 19, 459–462.

    Article  PubMed  CAS  Google Scholar 

  • Patelski, J. (1964): Esteraza cholesterolowa tgtnicy glównej (Cholesterol esterase of the aorta). Panstwowy Zaklad Wydawnictw Lekarskich, Warszawa.

    Google Scholar 

  • Patelski, J., Bowyer, D. E., Howard, A. N., and Gresham, G. A. (1968): Changes in phospholipase A, lipase and cholesterol esterase activity in the aorta in experimental atherosclerosis in the rabbit and rat. J. Atheroscler. Res. 8, 221–228.

    Article  CAS  Google Scholar 

  • Patelski, J., Bowyer, D. E., Howard, A. N., Jennings, I. W., Thorne, C. J. R., and Gresham, G. A. (1970): Modification of enzyme activities in experimental atherosclerosis in the rabbit. Atherosclerosis 12, 41–53.

    Article  PubMed  CAS  Google Scholar 

  • Patelski, J., Pniewska, B., Piorunska, M., and Obrgbska, M. (1975): The arterial acyl-CoA: Cholesterol acyltransferase and cholesterol ester hydrolase activities. In vitro effect of substrates with fatty acid of different chain length and saturation. Atherosclerosis 22, 287–291.

    Google Scholar 

  • Patelski, J. (1976): Arterial metabolism of cholesteryl esters. Mechanism of action of polyunsaturated phosphatidylcholine. In “Phosphatidylcholine” ( H. Peeters, ed.), pp. 201–210. Springer Verlag, Berlin, Heidelberg, New York.

    Chapter  Google Scholar 

  • Patelski, J., and Piorunska, M. (1977a): Cholesterol ester: lysolecithin acyltransferase activity of the aorta. In “ Atherosclerosis Metabolic, Morphologic, and Clinical Aspects” (G. W. Manning, and M. D. Haust, eds.), Proceedings of the 1975 International Workshop-Conference on Atherosclerosis (London, Ontario, Canada), pp. 303–305. Plenum Press, New York.

    Google Scholar 

  • Patelski, J., Pniewska-Plotast, B., Majewski, W., and Zapalski, S. (1977b): Lipid composition and enzyme activities of human arteriosclerotic femoral and iliac arteries. Enzyme 22, 412–415.

    PubMed  CAS  Google Scholar 

  • Szendzikowski, S., Patelski, J., and Pearse, A. G. E. (1961/62): The influence of cholinesterase inhibitors on the lipolytic activity of rat aorta. Enzyrnol. biol. clin. 1, 125–137.

    Google Scholar 

  • Waligóra, Z., Patelski, J., Brown, B. D., and Howard, A. N. (1975): Effect of a hypercholesterolaemic diet and a single injection of polyunsaturated phosphatidyl choline solution on the activities of lipolytic enzymes, acyl-CoA synthetase and acyl-CoA: cholestrol acyltransferase in rabbit tissues. Biochem. Pharmacol. 24, 2263–2267.

    Article  PubMed  Google Scholar 

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© 1978 Springer Fachmedien Wiesbaden

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Patelski, J. (1978). Enzyme — Substrate — Product Interactions in the Metabolism and Accumulation of Lipids in the Arterial Wall. In: International Symposium State of Prevention and Therapy in Human Arteriosclerosis and in Animal Models. Abhandlungen der Rheinisch-Westfälischen Akademie der Wissenschaften. VS Verlag für Sozialwissenschaften, Wiesbaden. https://doi.org/10.1007/978-3-663-06754-2_43

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  • DOI: https://doi.org/10.1007/978-3-663-06754-2_43

  • Publisher Name: VS Verlag für Sozialwissenschaften, Wiesbaden

  • Print ISBN: 978-3-531-05077-5

  • Online ISBN: 978-3-663-06754-2

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