Abstract
Thirty patients with multiple sclerosis (12 males and 18 females) presenting symptomatic urinary tract infections caused by severe multiresistant hospital organisms were selected for an open study on the efficacy and safety of ciprofloxacin. All patients had neurogenic bladder dysfunction and urinary tract infection, generally of nosocomial origin. Four patients were treated for pyelonephritis and 26 for cystitis. All presented with one or more signs or symptoms of urinary tract infection, such as fever (above 38.5 °C), flank pain, chills, urinary incontinence, dysuria and voiding frequency. Nineteen patients had had an indwelling bladder catheter for more than two months, and 13 had been previously treated for the same infection by other antimicrobial agents, e.g. cephalosporins and aminolgycosides. All patients underwent a complete urinalysis with microscopic examination and urine cultures and cornprehensive blood analysis (including ESR, hematology, creatinine, alkaline phosphatase, SGOT, SGPT, LDH, and total bilirubin) 48h before, on the third and the seventh day of treatment, and one and four weeks after therapy.
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© 1986 Springer Fachmedien Wiesbaden
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Van Poppel, H., Wegge, M., Dammekens, H., Chysky, V. (1986). Ciprofloxacin in the Treatment of Urinary Tract Infection in Patients with Multiple Sclerosis. In: Neu, H.C., Reeves, D.S. (eds) Ciprofloxacin. Current Topics in Infectious Diseases and Clinical Microbiology, vol 1. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01930-5_36
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DOI: https://doi.org/10.1007/978-3-663-01930-5_36
Publisher Name: Vieweg+Teubner Verlag, Wiesbaden
Print ISBN: 978-3-663-01931-2
Online ISBN: 978-3-663-01930-5
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