Abstract
Ciprofloxacin is a new synthetic 4-quinolone with marked antibacterial activity against a wide spectrum of aerobic gram-negative bacteria (1). In view of its in vitro activity ciprofloxacin shows great potential as an antibiotic for oral treatment of infections caused by resistant gram-negative organisms (2). The lack of cross-resistance with other groups of agents such as beta-lactam antibiotics and aminoglycosides is advantageous particularly since no plasmid-mediated resistance has been found (3).
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References
King, A., Shannon, K., Phillips, I.: The in vitro activities of enoxacin and ofloxacin compared with that of ciprofloxacin. Journal of Antimicrobial Chemotherapy 1985, 15: 551–558.
Palton, W. N., Smith, G. N., Leyland, M. J., Geddes, A. M.: Multiply resistant Salmonella typhimurium septicaemia in an immunocompromised patient successfully treated with ciprofloxacin. Journal of Antimicrobial Chemotherapy 1985, 16: 667–669.
Smith, J. T.: Mutational resistance to 4-quinolone antibacterial agents. European Journal of Clinical Microbiology 1984, 3: 347–350.
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© 1986 Springer Fachmedien Wiesbaden
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Mehtar, S., Drabu, Y., Blakemore, P. (1986). Ciprofloxacin in the Treatment of Infections Caused by Gentamicin-Resistant Gram-Negative Bacteria. In: Neu, H.C., Reeves, D.S. (eds) Ciprofloxacin. Current Topics in Infectious Diseases and Clinical Microbiology, vol 1. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01930-5_35
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DOI: https://doi.org/10.1007/978-3-663-01930-5_35
Publisher Name: Vieweg+Teubner Verlag, Wiesbaden
Print ISBN: 978-3-663-01931-2
Online ISBN: 978-3-663-01930-5
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