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Concentrations of Ciprofloxacin in Serum and Prostatic Tissue in Patients Undergoing Transurethral Resection

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Part of the book series: Current Topics in Infectious Diseases and Clinical Microbiology ((CTIDCM,volume 1))

Abstract

Transurethral resection (TUR) is the most common operation for treating bladder outflow obstruction due to hyperplasia or cancer of the prostate. TUR is a safe operation (mortality less than 1%), but severe infectious complications such as septicemia and upper urinary tract infections may jeopardize postoperative recovery. Short courses of therapy with appropriate antimicrobial agents significantly reduce the frequency of these complications and of postoperative bacteriuria in such patients, as compared to patients receiving no antibiotic (1). By virtue of its antimicrobial activity ciprofloxacin is a suitable agent for such short courses of therapy. The aim of the following study was to determine whether adequate serum and prostatic tissue concentrations of ciprofloxacin were achieved after oral administration of the drug to elderly men undergoing TUR.

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References

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H. C. Neu D. S. Reeves

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© 1986 Springer Fachmedien Wiesbaden

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Grabe, M., Forsgren, A., Björk, T. (1986). Concentrations of Ciprofloxacin in Serum and Prostatic Tissue in Patients Undergoing Transurethral Resection. In: Neu, H.C., Reeves, D.S. (eds) Ciprofloxacin. Current Topics in Infectious Diseases and Clinical Microbiology, vol 1. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01930-5_25

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  • DOI: https://doi.org/10.1007/978-3-663-01930-5_25

  • Publisher Name: Vieweg+Teubner Verlag, Wiesbaden

  • Print ISBN: 978-3-663-01931-2

  • Online ISBN: 978-3-663-01930-5

  • eBook Packages: Springer Book Archive

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