Abstract
Ciprofloxacin, a quinolone derivative of carboxylic acid, has a spectrum of antimicrobial activity that includes the Enterobacteriaceae, Staphylococcus aureus and Pseudomonas aeruginosa (1). It may therefore prove useful, alone or in combination, in the prophylaxis or treatment of infections in patients undergoing abdominal surgery. Intraperitoneal and serum levels were determined in these patients at varying times following a 100 mg intravenous dose of ciprofloxacin.
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References
Wise, R., Andrews, J. M., Edwards, L. J.: In vitro activity of Bay 09867, a new quinoline derivate, compared with those of other antimicrobial agents. Antimicrobial Agents and Chemotherapy 1983, 23: 559–564.
Wise, R., Lockley, R. M., Webberly, M., Dent, J.: Pharmacokinetics of intravenously administered ciprofloxacin. Antimicrobial Agents and Chemotherapy 1984, 26: 208–210.
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© 1986 Springer Fachmedien Wiesbaden
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Lockley, M.R., Waldron, R., Wise, R., Donovan, I.A. (1986). Intraperitoneal Penetration of Ciprofloxacin. In: Neu, H.C., Reeves, D.S. (eds) Ciprofloxacin. Current Topics in Infectious Diseases and Clinical Microbiology, vol 1. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01930-5_24
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DOI: https://doi.org/10.1007/978-3-663-01930-5_24
Publisher Name: Vieweg+Teubner Verlag, Wiesbaden
Print ISBN: 978-3-663-01931-2
Online ISBN: 978-3-663-01930-5
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