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Cobalamine, einschließlich Vitamin und Coenzym B12

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Book cover Bioanorganische Chemie

Part of the book series: Teubner Studienbücher Chemie ((TSBC))

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Zusammenfassung

Coenzym B12 und die davon abgeleiteten Derivate (3.1), einschließlich des Vitamins B12, eignen sich aus mehreren Gründen als Einführungsbeispiel für die bioanorganische Chemie. Zum einen sind im historischen Rückblick einige Meilensteine in der Entwicklung des gesamten Gebietes mit dem Vitamin B12 und später dem Coenzym verknüpft gewesen; dies betrifft unter anderem die therapeutische Nutzung, die Spurenelementbestimmung, die Anwendung chromatographischer Reinigungsmethoden, die kristallographische Strukturaufklärung und das Verhältnis zwischen enzymatischer und coenzymatischer Reaktivität. Weiter haben die moderne Naturstoffsynthese und die metallorganische Chemie von der Beschäftigung mit dem B12-System profitiert.

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Authors
  1. Prof. Dr. phil. nat. Wolfgang Kaim
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  2. Dr. rer. nat. Brigitte Schwederski
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© 2005 Springer Fachmedien Wiesbaden

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Kaim, W., Schwederski, B. (2005). Cobalamine, einschließlich Vitamin und Coenzym B12. In: Bioanorganische Chemie. Teubner Studienbücher Chemie. Vieweg+Teubner Verlag, Wiesbaden. https://doi.org/10.1007/978-3-663-01605-2_3

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