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Muskelaktivität – Muskelinaktivität: anti-nozizeptive oder pro-nozizeptive Körperstrukur

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Sensomotorik und Schmerz

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Zusammenfassung

Muskelaktivität prägt den eutroph-hypertrophen, antiinvolutiven, antientzündlichen und antinozizeptiven Körper. Lern-, Ausdauer- und Krafttraining führen zu nicht austauschbaren Anpassungen. Aus der Sicht des Schmerzes werden die Mikrozirkulation, die zentrale Schmerzhemmung, die Schmerzschwellen und die Schmerztoleranz entwickelt. Nur die aktive Muskulatur ist ein endokrines, para- und autokrines Organ und der Hauptregulator systemischer antientzündlicher Prozesse. Physische Inaktivität als globaler Faktor der Atrophie, Degeneration und proentzündlicher Prozesse bedeutet Dekonditionierung mit dem Hauptmerkmal permanente chronische systemische sterile Low-grade-Entzündung. Ergebnis sind die Erkrankungen der „diseasome of physical inactivity“ und die primären Arthrosen. Sie repräsentieren eine inaktivitätsbedingte atrophisch-degenerative, involutive, proentzündliche, pronozizeptive Struktur. Chronische Schmerzen inklusive peripherer und zentraler Sensibilisierung beruhen darauf.

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    Wolfgang Laube

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Laube, W. (2020). Muskelaktivität – Muskelinaktivität: anti-nozizeptive oder pro-nozizeptive Körperstrukur. In: Sensomotorik und Schmerz. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-60512-7_5

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