Skip to main content
SpringerLink
Log in

Antiepileptika

  • Chapter
  • First Online:
Book cover Arzneiverordnungs-Report 2019

  • 2925 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Ben-Menachem E, Biton V, Jatuzis D, Abou-Khalil B, Doty P, Rudd GD (2007) Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 48:1308–1317

    Article  CAS  Google Scholar 

  • Beydoun A (1999) Monotherapy trials with gabapentin for partial epilepsy. Epilepsia 40(Suppl 6):S13–S16

    Article  CAS  Google Scholar 

  • Brodie MJ (2004) Pregabalin as adjunctive therapy for partial seizures. Epilepsia 45(Suppl 6):19–27

    Article  CAS  Google Scholar 

  • Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke HJ (2007) Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Baillieres Clin Neurol 68:402–408

    CAS  Google Scholar 

  • Carmichael K, Pulman J, Lakhan SE, Parikh P, Marson AG (2013) Zonisamide add-on for drug-resistant partial epilepsy. Cochrane Database Syst Rev 2013 Dec 19; 12: CD001416

    Google Scholar 

  • Costa J, Fareleira F, Ascenção R, Borges M, Sampaio C, Vaz-Carneiro A (2011) Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis. Epilepsia 52:1280–1291

    Article  Google Scholar 

  • Deutsche Gesellschaft für Neurologie (2017) Leitlinien für Diagnostik und Therapie in der Neurologie. Erster epileptischer Anfall und Epilepsien im Erwachsenenalter (Internet: www.dgn.org/leitlinien)

    Google Scholar 

  • Dooley M, Plosker GL (2000) Levetiracetam. A review of its adjunctive use in the management of partial onset seizures. Drugs 60:871–893

    Article  CAS  Google Scholar 

  • Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M (2015) Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 14:162–173

    Article  CAS  Google Scholar 

  • Gabapentin Diabetic Neuropathy Study Group, Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, et al for the Gabapentin Diabetic Neuropathy Study Group (1998) Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus. JAMA 280:1831–1836

    Article  Google Scholar 

  • Gamble CL, Williamson PR, Marson AG (2006) Lamotrigine versus carbamazepine monotherapy for epilepsy. Cochrane Database Syst Rev 25(1):CD001031

    Google Scholar 

  • Goa KL, Ross SR, Chrisp P (1993) Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 46:152–176

    Article  CAS  Google Scholar 

  • Hitiris N, Brodie MJ (2006) Modern antiepileptic drugs: guidelines and beyond. Curr Opin Neurol 19:175–180

    PubMed  Google Scholar 

  • Kanner AM, Ashman E, Gloss D, Harden C, Bourgeois B, Bautista JF, Abou-Khalil B, Burakgazi-Dalkilic E, Llanas Park E, Stern J, Hirtz D, Nespeca M, Gidal B, Faught E, French J (2018) Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs I: treatment of new-onset epilepsy: report of the guideline development, dissemination, and implementation subcommittee of the American academy of neurology and the American epilepsy society. Neurology 91:74–81

    Article  CAS  Google Scholar 

  • Koch MW, Polman SK (2009) Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures. Cochrane Database Syst Rev 2009 Oct 7; (4): CD006453

    Google Scholar 

  • LaRoche SM, Helmers SL (2004) The new antiepileptic drugs: scientific review. JAMA 291:605–614

    Article  CAS  Google Scholar 

  • Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B (2004) The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. PNAS 101:9861–9866

    Article  CAS  Google Scholar 

  • Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJL, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DS, Smith PEM, Tudor Smith C, Vanoli A, Williamson PR, SANAD Study group (2007a) The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet 369:1000–1015

    Article  CAS  Google Scholar 

  • Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJL, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DS, Smith PEM, Tudor Smith C, Vanoli A, Williamson PR, SANAD Study group (2007b) The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalized and unclassifiable epilepsy: an unblinded randomized controlled trial. Lancet 369:1016–1026

    Article  CAS  Google Scholar 

  • Mbizvo GK, Dixon P, Hutton JL, Marson AG (2012) Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review. Cochrane Database Syst Rev 2012 Sep 12; 9: CD001901

    Google Scholar 

  • Milburn-McNulty P, Powell G, Sills GJ, Marson AG (2014) Sulthiame monotherapy for epilepsy. Cochrane Database Syst Rev 2014 Mar 9; 3: CD010062

    Google Scholar 

  • Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ (2009) Pregabalin for acute and chronic pain in adults. Cochrane Database Syst Rev 2009 Jul 8; (3): CD007076

    Google Scholar 

  • Morello CM, Leckband SG, Stoner CP, Moorhouse DF, Sahagian GA (1999) Randomized double-blind study comparing the efficacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain. Arch Intern Med 159:1931–1937

    Article  CAS  Google Scholar 

  • National Institute for Health and Care Excellence (NICE) (2018): Epilepsies: the diagnosis and management. Clinical guideline CG137. Published: 11 January 2012, last updated April 2018. Internet: https://www.nice.org.uk/guidance/cg137

  • Nunes VD, Sawyer L, Neilson J, Sarri G, Cross JH (2013) Profile of lacosamide and its role in the long-term treatment of epilepsy: a perspective from the updated NICE guideline. Neuropsychiatr Dis Treat 9:467–476

    Article  CAS  Google Scholar 

  • Perucca E, Yasothan U, Clincke G, Kirkpatrick P (2008) Lacosamide. Nat Rev Drug Discov 7:973–974

    Article  CAS  Google Scholar 

  • Pulman J, Jette N, Dykeman J, Hemming K, Hutton JL, Marson AG (2014) Topiramate add-on for drug-resistant partial epilepsy. Cochrane Database Syst Rev 2014 Feb 25; 2: CD001417

    Google Scholar 

  • Stephen LJ, Brodie MJ (2017) Brivaracetam: a novel antiepileptic drug for focal-onset seizures. Ther Adv Neurol Disord 11:1756285617742081

    PubMed  PubMed Central  Google Scholar 

  • Thijs RD, Surges R, O’Brien TJ, Sander JW (2019) Epilepsy in adults. Lancet 393:689–701

    Article  Google Scholar 

  • Tomson T, Battino D, Perucca E (2016) Valproic acid after five decades of use in epilepsy: time to reconsider the indications of a time-honoured drug. Lancet Neurol 15:210–218

    Article  CAS  Google Scholar 

  • Veroniki AA, Cogo E, Rios P, Straus SE, Finkelstein Y, Kealey R, Reynen E, Soobiah C, Thavorn K, Hutton B, Hemmelgarn BR, Yazdi F, D’Souza J, MacDonald H, Tricco AC (2017) Comparative safety of anti-epileptic drugs during pregnancy: a systematic review and network meta-analysis of congenital malformations and prenatal outcomes. BMC Med 15(1):95

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pharmakologisches Institut der Universität Heidelberg, Heidelberg, Deutschland

    Prof. em. Dr. med. Ulrich Schwabe

Authors
  1. Prof. em. Dr. med. Ulrich Schwabe
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ulrich Schwabe .

Editor information

Editors and Affiliations

  1. Pharmakologisches Institut, Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany

    Ulrich Schwabe

  2. Köln, Nordrhein-Westfalen, Germany

    Dieter Paffrath

  3. Arzneimittelkommission der deutschen Ärzteschaft (AkdÄ), Berlin, Berlin, Germany

    Wolf-Dieter Ludwig

  4. Wissenschaftliches Institut der AOK, Berlin, Berlin, Germany

    Jürgen Klauber

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Schwabe, U. (2019). Antiepileptika. In: Schwabe, U., Paffrath, D., Ludwig, WD., Klauber, J. (eds) Arzneiverordnungs-Report 2019. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59046-1_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-59046-1_17

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-59045-4

  • Online ISBN: 978-3-662-59046-1

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation