This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsLiteratur
Andrade S, Bartels DB, Lange R, Sandford L, Gurwitz J (2016) Safety of metamizole: a systematic review of the literature. J Clin Pharm Ther 41:459–477
Arzneimittelkommission der deutschen Ärzteschaft (1986) Bundesgesundheitsamt schränkt Anwendungsgebiet von Metamizol-haltigen Monopräparaten ein. Dtsch Arztebl 83:3267
Arzneimittelkommission der deutschen Ärzteschaft (2007a) Empfehlungen zur Therapie von Tumorschmerzen. AVP-Sonderheft Therapieempfehlungen, 3. Auflage. http://www.akdae.de/35/10/66-Tumorschmerzen-2007-3Auflage.pdf
Arzneimittelkommission der deutschen Ärzteschaft (2007b) Leberschäden unter Flupirtin. Dtsch Arztebl 104:A3200
Arzneimittelkommission der deutschen Ärzteschaft (2012) Die unkritische Anwendung von Fentanylpflastern erhöht das Risiko für schwerwiegende Nebenwirkungen. Dtsch Arztebl 109:A724–A725
Bornemann-Cimenti H, Wejbora M, Szilagyi I, Sandner-Kiesling A (2013) Fentanyl zur Behandlung von tumorbedingten Durchbruchschmerzen. Dtsch Arztebl 110:271–277
Boscarino JA, Rukstalis M, Hoffmann SN, Han JJ, Erlich PM, Gerhard GS, Steward WF (2010) Risk factors for drug dependence among out-patients on opioid therapy in a large US health-care system. Addiction 105:1776–1782
Brat GA, Agniel D, Beam A, Yorkgitis B, Bickel M, Homer M, Fox KP, Knecht DB, McMahill-Walraven CN, Palmer N, Kohane I (2018) Postsurgical prescriptions for opioid naïve patients and association with overdose and misuse: retrospective cohort study. Brit Med J 360:j5790
Budd K (1990) Experience with partial antagonists in the treatment of cancer pain. In: Doyle D (Hrsg) Opioids in the treatment of cancer pain. International congress and symposium series, Bd. 146. Royal Society of Medicine, S 51–54
Chaparro LE, Furlan AD, Deshpande A, Mailis-Gagnon A, Atlas S, Turk DC (2014) Opioids compared with placebo or other treatments for chronic low back pain: an update of the Cochrane review. Spine 39:556–563
Dahan A, Yassen A, Bijl H, Romberg R, Sarton E, Teppema L, Olofsen E, Danhof M (2005) Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats. Br J Anaesth 94:825–834
Devulder J (2010) Flupirtine in pain management: pharmacological properties and clinical use. CNS Drugs 24:867–881
Drover DR, Angst MS, Valle M, Ramaswamy B, Naidu S, Stanski DR, Verotta D (2002) Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers. Anesthesiology 97:827–836
European Medicines Agency (2018) Widerruf des Schmerzmittels Flupirtin bestätigt. Weiterhin Fallberichte über schwere Leberschädigungen trotz vorheriger Anwendungsbeschränkungen. https://www.ema.europa.eu/en/medicines/human/referrals/flupirtine-containing-medicinal-products#overview-section
Faria J, Barbosa J, Moreira R, Queirós O, Dinis-Oliveira RJ (2018) Comparative pharmacology and toxicology of tramadol and tapentalol. Eur J Pain 22:827–844
Frampton JE (2010) Tapentadol immediate release: a review of its use in the treatment of moderate to severe acute pain. Drugs 70:1719–1743
Furlan AD, Sandoval JA, Mailis-Gagnon A, Tunks E (2006) Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects. CMAJ 174:1589–1594
Garbe E, Jobski K, Schmid U (2012) Utilisation of transdermal fentanyl in Germany from 2004 to 2006. Pharmacoepidemiol Drug Saf 21:191–198
Hanks GW, De Conno F, Cherny N, Expert Working Group of the Research Network of the European Association for Palliative Care (2001) Morphine and alternative opioids in cancer pain: the EAPC recommendations. Br J Cancer 84:587–593
Jacox A, Carr DB, Payne R, Agency for Health Care Policy and Research (AHCPR) Pharmacological Management (1994) Recommendations. In: Management of cancer pain. Clinical Practice Guideline No 9. AHCPR Publication, Bd. 94-0592. U.S. Department of Health and Human Services, Public Health Service, Rockville
Kassenärztliche Bundesvereinigung (2012a) Oxycodon/Naloxon. Wirkstoff aktuell Ausgabe 6/2012. http://www.akdae.de/Arzneimitteltherapie/WA/Archiv/Oxycodon-Naloxon.pdf
Kassenärztliche Bundesvereinigung (2012b) Tapentadol. Wirkstoff aktuell Ausgabe 3/2012. http://www.akdae.de/Arzneimitteltherapie/WA/Archiv/Tapentadol.pdf
Kaye AD, Jones MR, Kaye AM, Ripoll JG, Galan V, Beakley BD, Calixto F, Bolden JL, Urman RD, Manchikanti L (2017) Prescription opioid abuse in chronic pain: an updated review of opioid abuse predictors and strategies to curb opioid abuse: part 1. Pain Physician 20:93–109
Langford RM, Knaggs R, Farguhar-Smith P, Dickenson AH (2016) Is tapentalol different from classical opioids? A review of the evidence. Brit J Pain 10:217–221
Lauche R, Klose P, Radbruch R, Welsch P, Häuser W (2015) Opioids in chronic noncancer pain – are opioids superior to nonopioid analgesics? A systematic review and metaanalysis to efficacy, tolerability and safety in randomized head-to-head comparisons of opioids versus nonopioid analgesics of at least four weeks duration. Schmerz 29:85–95
Meissner W, Leyendecker P, Mueller-Lissner S, Nadstawek J, Hopp M, Ruckes C, Wirz S, Fleischer W, Reimer K (2009) A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation. Eur J Pain 13:56–64
Quigley C (2002) Hydromorphone for acute and chronic pain. Cochrane Database Syst Rev 2002 (1): CD003447
Radbruch L, Elsner F (2005) Palliative Schmerztherapie, Cannabinoide. Internist 46:1105–1114
Ripamonti C, Fagnoni E, Campa T, Brunelli C, De Conno F (2006) Is the use of transdermal fentanyl inappropriate according to the WHO guidelines and the EAPC recommendations? A study of cancer patients in Italy. Support Care Cancer 14:400–407
Schubert I, Ihle P, Sabatowski R (2013) Zunahme der Opioidverordnungen in Deutschland zwischen 2000 und 2011. Dtsch Arztebl 110:45–51
Shah RR (2019) Metamizole (dipyrone)-induced agranulocytosis: Does the risk vary according to ethnicity? J Clin Pharm Ther 44:129–133
Sullivan MD, Edlund MJ, Fan MY, Devries A, Brennan Braden J, Martin BC (2008) Trends in use of opioids for non-cancer pain conditions 2000–2005 in commercial and Medicaid insurance plans: the TROUP study. Pain 138:440–449
The Pain Society (2004) Recommendations for the appropriate use of opioids for persistent non-cancer pain. http://www.britishpainsociety.org/pdf/opioids_doc_2004.pdf (Erstellt: 03.2004) (A consensus statement prepared on behalf of the Pain Society, the Royal College of Anaesthetists, the Royal College of General Practitioners and the Royal College of Psychiatrists)
Wiffen PJ, Derry S, Naessens K, Bell RF (2015) Oral tapentalol for cancer pain. Cochrane Database Syst Rev 2015: CD011460
Wilcock A (2009) Prolonged-release naloxone can cause systemic opioid withdrawal. Eur J Pain 1001(2009):13
World Health Organization (WHO) (1986) Cancer pain relief. World Health Organization Publications, Geneva
World Health Organization (WHO) (1996) Cancer pain relief, 2. Aufl. World Health Organization Publications, Geneva
Zhang WY, Po AL (1996) Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain – a metaanalysis. J Clin Pharm Ther 21:261–282
Zhang WY, Po AL (1997) Do codeine and caffeine enhance the analgesic effect of aspirin? A systematic overview. J Clin Pharm Ther 22:79–97
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Böger, R.H., Schmidt, G. (2019). Analgetika. In: Schwabe, U., Paffrath, D., Ludwig, WD., Klauber, J. (eds) Arzneiverordnungs-Report 2019. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59046-1_10
Download citation
DOI: https://doi.org/10.1007/978-3-662-59046-1_10
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-59045-4
Online ISBN: 978-3-662-59046-1
eBook Packages: Medicine (German Language)