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Genetics in Rotator Cuff Tears: First Steps to the Future

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Rotator Cuff Across the Life Span

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Abstract

The etiology of rotator cuff disease is multifactorial with extrinsic and intrinsic tendon factors being proposed to explain it. But also, prior studies provide preliminary evidence for genetic and familial predisposition to rotator cuff tears. Genetics are probably the key to the future, although data is still scarce, in its very beginning, and poorly understood.

Identifying genetic differences associated with rotator cuff tears could help our understanding of the disease, early detection, and assistance to individuals at risk for development of nontraumatic tears and provide potential future gene therapies.

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Author information

Authors and Affiliations

  1. Shoulder and Elbow Group of Sports Traumatology Center, Federal University of São Paulo, São Paulo, Brazil

    Carina Cohen, Eduardo A. Figueiredo & Benno Ejnisman

  2. Morphology and Genetic Department, Federal University of São Paulo, São Paulo, Brazil

    Mariana F. Leal

Authors
  1. Carina Cohen
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  2. Eduardo A. Figueiredo
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  3. Mariana F. Leal
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  4. Benno Ejnisman
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Editors and Affiliations

  1. Orthopaedic Sportsmedicine, University of Munich (TUM), Orthopaedic Sportsmedicine, Munich, Bayern, Germany

    Andreas B. Imhoff

  2. Department of Orthopaedics, Tulane University School of Medicine, Department of Orthopaedics, New Orleans, LA, USA

    Felix H. Savoie III

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Cohen, C., Figueiredo, E.A., Leal, M.F., Ejnisman, B. (2019). Genetics in Rotator Cuff Tears: First Steps to the Future. In: Imhoff, A.B., Savoie, F.H. (eds) Rotator Cuff Across the Life Span. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58729-4_5

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  • DOI: https://doi.org/10.1007/978-3-662-58729-4_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-58728-7

  • Online ISBN: 978-3-662-58729-4

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