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Beurteilung und Therapie der Lutealphase

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Reproduktionsmedizin

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Zusammenfassung

Die Lutealphase ist die zweite Zyklushälfte und wird durch Umwandlung des dominanten Follikels zum Corpus luteum nach Freisetzung der Eizelle bei der Ovulation charakterisiert. Die Progesteronwirkung am Endometrium ermöglicht Eintritt und Erhalt einer Schwangerschaft. Eine unzureichende Progesteronsekretion oder -wirkung kennzeichnet eine Lutealphaseninsuffizienz. Dies ist als Folge einer vorausgegangenen Reifungsstörung des Follikels zu verstehen und – wann immer möglich – ursächlich zu behandeln. Aufgrund der fehlenden Validität von Progesteronmessung oder Endometriumbiopsie erfolgt die Diagnose klinisch anhand eines auffälligen Zyklusmusters mit verkürzter zweiter Zyklushälfte und/oder prämenstruellen Spottings. Nach jeder kontrollierten ovariellen Stimulation im Rahmen einer assistierten Reproduktion muss eine Lutealphasensubstitution erfolgen.

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Authors and Affiliations

  1. Facharzt-Zentrum für Kinderwunsch, Pränatale Medizin, Endokrinologie und Osteologie, amedes experts Hamburg, Hamburg, Deutschland

    Barbara Sonntag

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  1. Barbara Sonntag
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Correspondence to Barbara Sonntag .

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Editors and Affiliations

  1. Facharzt-Zentrum für Kinderwunsch Pränatale Medizin, Endokrinologie und Osteologie Hamburg GmbH, amedes experts, Hamburg, Germany

    Klaus Diedrich

  2. SYNLAB Holding Deutschland GmbH, Augsburg, Germany

    Michael Ludwig

  3. Sektion für gynäkologische Endokrinologie und Reproduktionsmedizin, Universitätsklinikum Schleswig-Holstein – Campus Lübeck, Lübeck, Germany

    Georg Griesinger

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Sonntag, B. (2020). Beurteilung und Therapie der Lutealphase. In: Diedrich, K., Ludwig, M., Griesinger, G. (eds) Reproduktionsmedizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57636-6_8

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  • DOI: https://doi.org/10.1007/978-3-662-57636-6_8

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  • Publisher Name: Springer, Berlin, Heidelberg

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  • Online ISBN: 978-3-662-57636-6

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